LSI DTCs 2007 - Graduate Academy for tissue engineering and regenerative medicine
LSI DTCs 2007 - Graduate Academy for tissue engineering and regenerative medicine
批准号:
EP/F500513/1
负责人:
John Fisher
金额:
$901.3万
依托单位:
依托单位国家:
英国
项目类别:
Training Grant
财政年份:
2008
资助国家:
英国
项目状态:
已结题
起止时间:
2008 至 --
中文摘要
定义:介于工程/物理科学、生命科学和医学之间的一个快速发展的领域。包括:-细胞疗法(包括干细胞)、三维细胞/基质结构、生物活性支架、再生设备、用于药物发现和临床前研究的体外组织模型。社会和经济需求包括:随着对积极生活方式的期望和政府对更长工作寿命的要求,老龄化人口的寿命增加。需要降低医疗成本,缩短住院时间,实现更快的康复在药品和医疗设备之间的界面上的紧急颠覆性工业部门需要相关实验室生物系统,用于在早期开发阶段筛选和选择药物,以及减少、改进、取代体内测试。转化障碍和行业需求:组织工程/再生医药行业需要增加训练有素的多学科人员,以转化基础研究、交付新产品开发、提高制造和加工能力、开发临床前试验方法以及制定标准,并在动态的监管环境中开展工作。来自N8再生医学行业研讨会的证据。学术需求:一个迅速崛起的具有国际竞争力的交叉学科领域,需要新的血液
英文摘要
Definition: A rapidly developing area at the interfaces of engineering/physical sciences, life sciences and medicine. Includes:- cell therapies (including stem cells), three dimensional cell/ matrix constructs, bioactive scaffolds, regenerative devices, in vitro tissue models for drug discovery and pre-clinical research.Social and economic needs include:Increased longevity of the ageing population with expectations of an active lifestyle and government requirements for a longer working life.Need to reduce healthcare costs, shorten hospital stays and achieve more rapid rehabilitationAn emergent disruptive industrial sector at the interface between pharmaceutical and medical devicesRequirement for relevant laboratory biological systems for screening and selection of drugs at theearly development stage, coupled with Reduction, Refinement, Replacement of in vivo testing. Translational barriers and industry needs: The tissue engineering/ regenerative medicine industry needs an increase in the number of trained multidisciplinary personnel to translate basic research, deliver new product developments, enhance manufacturing and processing capacity, to develop preclinical test methodologies and to develop standards and work within a dynamic regulatory environment. Evidence from N8 industry workshop on regenerative medicine.Academic needs: A rapidly emerging internationally competitive interdisciplinary area requiring new blood ---------------------
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
NSF/FDA SIR: 3D Human Stem Cell Cardiac Model for Cardiac Electrophysiology Medical Device Safety Assessment
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批准号:2129369
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项目类别:Standard Grant
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资助金额:$10.0万
-
财政年份:2022
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负责人:John Fisher
-
依托单位:
Collaborative Research: 4D Bioprinting of Near-infrared Light Responsive Smart Constructs for Pluripotent Stem Cell Derived Cardiomyocyte Engineering
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批准号:1856350
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项目类别:Standard Grant
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资助金额:$27.5万
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财政年份:2019
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负责人:John Fisher
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依托单位:
NSF/FDA Scholar In Residence: 3D Cell Adhesion Assay for Cellularized Scaffold Characterization and Enhancement
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批准号:1641087
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项目类别:Standard Grant
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资助金额:$16.11万
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财政年份:2017
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负责人:John Fisher
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依托单位:
Biohybrid Strategies for Decellularized Tissues
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批准号:1604742
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项目类别:Standard Grant
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资助金额:$30.74万
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财政年份:2016
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负责人:John Fisher
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依托单位:
NSF/FDA Scholar In Residence: 3D Printed Biomaterials for MSC Attachment and Targeted Differentiation
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批准号:1445700
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项目类别:Standard Grant
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资助金额:$12.67万
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财政年份:2015
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负责人:John Fisher
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依托单位:
2014 TERMIS-AM Conference in Washington, DC on December 13-16, 2014
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批准号:1439059
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项目类别:Standard Grant
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资助金额:$3.35万
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财政年份:2014
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负责人:John Fisher
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依托单位:
EPSRC Centre for Innovative Manufacturing in Medical Devices
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批准号:EP/K029592/1
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项目类别:Research Grant
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资助金额:$722.07万
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财政年份:2013
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负责人:John Fisher
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依托单位:
Shear Force Effects on Superficial Cartilage Regeneration
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批准号:1264517
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项目类别:Standard Grant
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资助金额:$30.98万
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财政年份:2013
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负责人:John Fisher
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依托单位:
NSF/FDA SIR: Biomaterials for MSC Adhesion and Enrichment
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批准号:1238398
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项目类别:Standard Grant
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资助金额:$12.26万
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财政年份:2012
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负责人:John Fisher
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依托单位:
Innovation and Knowledge Centre Regenerative Therapies and Devices Tranche 2 IKC RTD
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批准号:EP/J017620/1
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项目类别:Research Grant
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资助金额:$231.08万
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财政年份:2012
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负责人:John Fisher
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依托单位:
Innovation and Knowledge Centre Regenerative Therapies and Devices Tranche 1 IKC RTD
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批准号:EP/I019103/1
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项目类别:Research Grant
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资助金额:$351.82万
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财政年份:2011
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负责人:John Fisher
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依托单位:
REU Site: Molecular & Cellular Bioengineering
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批准号:1005123
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项目类别:Standard Grant
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资助金额:$30.0万
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财政年份:2010
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负责人:John Fisher
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依托单位:
Regenerative Therapies and Devices
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批准号:EP/G032483/1
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项目类别:Research Grant
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资助金额:$623.59万
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财政年份:2009
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负责人:John Fisher
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依托单位:
Programme Grant Application in Bio Tribology of Articular Cartilage and Substitution Interventions
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批准号:EP/G012172/1
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项目类别:Research Grant
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资助金额:$578.09万
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财政年份:2009
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负责人:John Fisher
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依托单位:
Leeds EPSRC Nanoscience and Nanotechnology Research Equipment Facility
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批准号:EP/F056311/1
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项目类别:Research Grant
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资助金额:$86.76万
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财政年份:2008
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负责人:John Fisher
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依托单位:
Functional Tissue Replacement and Substitution: Platform Grant
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批准号:EP/F043872/1
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项目类别:Research Grant
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资助金额:$110.75万
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财政年份:2008
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负责人:John Fisher
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依托单位:
Molecular and Cellular Bioengineering Research Experiences for Undergraduates (REU) Site
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批准号:0649052
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项目类别:Continuing Grant
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资助金额:$30.0万
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财政年份:2007
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负责人:John Fisher
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依托单位:
Self assembly of GAG-Functionalised Peptides into Proteoglycan-Like Molecules for Tissue Engineering
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批准号:EP/D070791/1
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项目类别:Research Grant
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资助金额:$55.8万
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财政年份:2007
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负责人:John Fisher
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依托单位:
Follow on: Self assembling biphasic gels and hydrogels for cartilage substitution therapies
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批准号:EP/E502725/1
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项目类别:Research Grant
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资助金额:$8.27万
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财政年份:2006
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负责人:John Fisher
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依托单位:
CAREER: Enhancing Cell Signaling in Heterogeneous Cell Populations - An Integrated Education and Research Study
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批准号:0448684
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项目类别:Continuing Grant
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资助金额:$0.0万
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财政年份:2005
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负责人:John Fisher
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依托单位:
国内基金
海外基金
基于“先安未受邪之地”理论研究胆固醇代谢重编程介导的肝脏预转移小生境DTCs免疫逃逸机制
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批准号:82575164
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项目类别:面上项目
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资助金额:51.00万元
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批准年份:2025
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负责人:朱 世杰
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依托单位:
播散肿瘤细胞(DTCs)与造血干细胞(HSCs)融合促进前列腺癌骨转移的分子机制
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批准号:81773146
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项目类别:面上项目
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资助金额:51.0万元
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批准年份:2017
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负责人:卢奕
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依托单位: