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Identification and characterisation of HLA-E restricted influenza A virus-specific CD8+ T cells

Identification and characterisation of HLA-E restricted influenza A virus-specific CD8+ T cells
HLA-E 限制性甲型流感病毒特异性 CD8 T 细胞的鉴定和表征
批准号:
nhmrc : 1110429
负责人:
Dr Emma Grant
金额:
$24.47万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2020-12-31

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中文摘要
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英文摘要
With seasonal epidemics and the continual threat of a pandemic, there is an urgent need for a one-shot universal vaccine that protects against different influenza strains. This can potentially be achieved by the activation of killer T cells. I will identify new virus targets presented by a highly conserved human protein. Killer T cell recognition of these targets may provide a unique opportunity to develop an improved vaccine.
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会议论文
The investigation of an unconventional Human Leukocyte Antigen molecule
  • 批准号:
    DE210101479
  • 项目类别:
    Discovery Early Career Researcher Award
  • 资助金额:
    $31.72万
  • 财政年份:
    2021
  • 负责人:
    Dr Emma Grant
  • 依托单位:
Identification and characterisation of HLA-E restricted influenza A virus-specific CD8+ T cells
  • 批准号:
    nhmrc : GNT1110429
  • 项目类别:
    Early Career Fellowships
  • 资助金额:
    $35.42万
  • 财政年份:
    2016
  • 负责人:
    Dr Emma Grant
  • 依托单位:
Understanding influenza-specific T cell immunity in the Indigenous and non-Indigenous populations
  • 批准号:
    nhmrc : 1055323
  • 项目类别:
    Postgraduate Scholarships
  • 资助金额:
    $3.28万
  • 财政年份:
    2013
  • 负责人:
    Dr Emma Grant
  • 依托单位:
海外基金