Liquid crystal-based sensor for real-time detection of O3, CO and CO2

描述(由申请人提供) 该项目的目标是开发一种启用GPS的多分析物传感器，可以检测和测量空气中存在的痕量气体，特别是臭氧、一氧化碳和二氧化碳气体的暴露。这种传感器是基于对液晶锚定到金属离子功能化表面的创新开发。在初步研究中，我们展示了识别选择性结合臭氧的金属组合的能力，以及设计产生特定于功能基团的指纹的多金属阵列的能力。我们还演示了使用这项新技术来快速(~10秒)测量暴露在ppb浓度下的有机磷化合物。我们创建的传感表面可以调节为可逆的，不受湿度的影响，并以剂量依赖的方式响应。这些数据有力地支持了PlatypusTM技术作为一种紧凑型、多分析物、现场可部署的个人设备的可行性，用于检测接触微量气体的情况。在这项提议中，我们将开发一个传感器子系统，并将其与启用GPS的组件集成在一起，这些组件跟踪和存储信息，如曝光程度、曝光时间和持续时间以及曝光事件的准确位置。我们计划的产品将允许简单地将数据上传到计算机，并将在现场条件下进行测试。需要这样一种产品来促进理解人类对环境暴露的敏感性。

DESCRIPTION (provided by applicant) The goal of this project is to develop a GPS-enabled multi-analyte sensor that can detect and measure exposure to trace gases present in air, specifically ozone, carbon monoxide and carbon dioxide gases. This sensor is based on the innovative exploitation of the anchoring of liquid crystals to a surface functionalized with metal ions. In preliminary studies we have demonstrated the ability to identify combinations of metals that selectively bind ozone and to design multi-arrays of metals that create fingerprints specific for functional groups. We also demonstrated the use of this new technology to rapidly (~ 10 seconds) measure exposure to ppb concentrations of an organophosphate compound. The sensing surfaces we created could be tuned to be reversible, were unaffected by humidity, and responded in a dose-dependent manner. These data strongly support the feasibility of PlatypusTM technology as the basis of a compact, multi-analyte, field deployable personal device for detection of exposure to trace gases. In this proposal we will develop a sensor subsystem and integrate it with GPS-enabled components that track and store information such as degree of exposure, time and duration of exposure and exact location of exposure events. Our intended product will allow simple uploading of the data to a computer and will be tested under field conditions. Such a product is needed to facilitate the understanding of human susceptibility to environmental exposures.