Neuroimaging Core

生物统计和数据管理核心将为研究提供统计和数据库支持 在SPOTRIAS中进行。这将包括在研究的统计方面进行合作和协商 设计和规划，数据库开发和维护，数据质量控制和监测，以及 数据分析和解释。该核心的具体目标是： 1.提供统计和计算专业知识的设计，规划，进行，分析， 报告与以下疾病相关的实验室实验、影像学研究、观察性研究和临床试验： SPOTRIAS项目。 2.为SPOTRIAS的整个团队提供统计和计算专业知识 调查人员通过"开门"咨询。 3.在电子病例报告表（eCRF）方面为SPOTRIAS研究者提供建议和支持 设计、数据收集、电子数据采集和数据管理系统开发， 数据质量控制。 4.与生物统计学家合作，向研究主要研究者提供报告，医学 监查员和数据安全和监查委员会（DSMB）。 5.提供统计咨询和合作方面的培训， 哈佛公共卫生学院的生物统计学和流行病学系， NINDS T32培训补助金，"神经统计学和神经流行病学培训。"

The Biostatistics and Data Management Core will provide the statistical and database support for research conducted in SPOTRIAS. This will include collaboration and consultation on the statistical aspects of study design and planning, database development and maintenance, data quality control and monitoring as well as data analysis and interpretation. The specific aims of this Core are: 1. To provide statistical and computational expertise for the design, planning, conduct, analysis, and reporting of laboratory experiments, imaging studies, observational studies, and clinical trials associated with SPOTRIAS Projects. 2. To provide ready access to statistical and computational expertise to the entire group ofSPOTRIAS investigators through "open door" consultation. 3. To advise and support SPOTRIAS investigators in the areas of electronic case report form (eCRF) design, data collection, electronic data capture and data management system (ECD&DM) development and data quality control. 4. To collaborate with Biostatisticians on provision of reports to study principal investigators, medical monitor, and the Data Safety and Monitoring Board (DSMB). 5. To provide training in statistical consultation and collaboration to pre- and post-doctoral students in the Biostatistics and Epidemiology Departments at Harvard School of Public Health who are supported by the NINDS T32 training grant, "Training in Neurostatistics and Neuroepidemiology."