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Leadership and Administration Core

领导和行政核心

基本信息

批准号：
7727536
负责人：
Nicole Denise Urban
金额：
$ 8.07万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-07-01 至 2014-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7727536
关键词：
Achievement Address Advertising Advocacy Advocate Affect Arts Award Awareness Biological Blood Blood specimen Cancer Advocacy Cancer Center Support Grant Cancer Patient Caring Charge Clinic Clinical Collaborations Commit Committee Members Communication Communities Community Outreach Community Physician Databases Dedications Detection Development Directories Discipline District of Columbia Early Diagnosis Educational workshop Electronics Encapsulated Enrollment Ensure Epidemiology Equipment and supply inventories Event Family Family member Feedback Fees Friends Funding Genomics Goals Grant Health Fairs High Risk Woman Hospitals Hour Image Immunology Immunotherapy Individual Informatics Institution Instruction International Internet Intervention Investments Joints Laboratories Leadership Learning Letters Life Link Location Logistics Mails Malignant Neoplasms Malignant neoplasm of ovary Medical Dictionaries Medical center Mentors Mentorship Methods Modeling Molecular Profiling Monitor Names Nature Neoadjuvant Therapy Newsletter Operations Research Organ Outcome Ovarian Pamphlets Participant Pathology Patient Care Patient advocacy Patients Pattern Persons Phase Phase I Clinical Trials Physicians&apos Offices Pilot Projects Population Principal Investigator Process Productivity Prostate Proteomics Public Health Publications Published Comment Published Directory Quality of life Recruitment Activity Recurrence Reporting Reproduction spores Research Research Activity Research Ethics Committees Research Personnel Research Project Grants Research Proposals Resource Allocation Resource Sharing Resources Review Committee Risk Role Schedule Science Scientific Evaluation Scientist Screening procedure Series Serum Markers Site Specialist Specific qualifier value Specimen Specimen Handling Statistical Methods Structure Suggestion Surgeon Survivors Testing Time Translating Translational Research Universities Update Woman Work Writing abstracting anticancer research base cancer care career development cost efficacy trial falls improved innovation interdisciplinary collaboration interest meetings member novel novel marker outreach patient advocacy group posters prevent programs repository research study response sample collection statistics success tool tumor web site

项目摘要

The goal of the Leadership and Administration Core is to ensure that translational goals of the POCRC are met and that resources are used effectively. The Leadership Core is responsible for ongoing evaluation of scientific and translational progress of all projects. If progress is not sufficient, the Executive Committee comprised of Dr. Nicole Urban, Principal Investigator, and co-principal investigators, Drs. Mary (Nora) Disis, Charles Drescher, Beth Karlan, Steve Collins, and Martin (Mac) Cheever, will take necessary action. The Executive Committee is also responsible for ensuring that cores meet the needs of projects without redundancy or confiict, providing scientific leadership, facilitafing Inter-SPORE communication, coordinafing collaborations, integrating POCRC and CCSG activities, and allocating SPORE resources. The,Leadership Core will be responsible for coordinating SPORE activities and assuring communication between the cores, projects and committees. Committees within the Leadership Core will include representation from members ofthe Patient Advocate Group to make certain that the POCRC constanfiy works towards achieving its translational goals and meeting the needs ofthe patient. The Leadership Core will provide overall guidance for the translational activities ofthe SPORE, building on established interdisciplinary collaborations. It will promote, oversee, and evaluate active interaction between the cores and the projects. Through the advisory boards and committees, the Leadership Core will provide the following functions: 1) overall management and coordination ofthe SPORE; 2) meet the scientific advisory needs of the individual research projects; 3) oversee, plan, and evaluate SPORE acfivifies including inter¿ SPORE activities; 4) promote, oversee, and evaluate interaction of cores and projects; 5) encourage, select, and guide developmental projects; 6) provide mentoring and career development; 7) manage, distribute, and re-allocate SPORE funds and other resources as appropriate; 8) oversee IRB activity; 9) ensure that scientific objectives can ultimately be translated to patient care; 10) initiate new activities in response to important translational research opportunities. To address the needs of the projects and the cores, experts in ovarian cancer, translational research, early detection/screening, epidemiology, genomics, immunology, statistical methods, informatics, and pathology have been identified and recruited to serve in the Leadership Core. Senior leaders with relevant expertise will interact with each other on substantive committees as well as provide mentorship to POCRC investigators who are experts in their own fields but less acquainted with other disciplines that are critical to career development in ovarian cancer translational research and the overall success ofthe POCR(Z;. RELEVANCE (See instructions): The goal of this ovarian SPORE is to demonstrate better strategies for 1) screening high-risk women using novel serum markers and state-of-the-art imaging without the need for another large trial, by integrating our Phase I trial results with reports from ongoing Phase III efficacy trials; 2) selecting women for neoadjuvant therapy by testing their blood for a resectability signature; and 3) immunizing women against their own tumors to prevent recurrence. Success in one or more of these efforts will significantly reduce the burden of ovarian cancer.

领导和行政核心的目标是确保POCRC的转化目标是有效的