Core B: Animal Models Core

核心 B：动物模型核心

• 批准号: 7751475
• 负责人: TIMOTHY R BILLIAR
• 金额: $ 29.23万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7751475
• 关键词: Animal Model; Biology; Disease; Equipment; Hemorrhagic Shock; Investigation; Ischemia; Modeling; Molecular Biology; Mus; Process; Rattus; Reperfusion Therapy; Reproducibility; Rodent; Shock; Source; Trauma

The purpose of the Animal Models Core is to provide a well-controlled and consistent source of rats and mice subjected to standardized hemorrhaghic shock and regional ischemia/reperfusion insults. By centralizing the equipment and expertise to carry out these rodent hemorrhagic shock models, we can maximize our efficiency and reproducibility in our investigation of this disease process and effectively compare the results from the five separate projects. RELEVANCE (See instnjctions): Animal models of trauma are essential to the study of the biology of mammolian trauma.

动物模型核心的目的是提供一个控制良好且一致的大鼠来源和 小鼠遭受标准化失血性休克和局部缺血/再灌注损伤。经过 集中设备和专业知识来开展这些啮齿动物失血性休克模型，我们可以 最大限度地提高我们调查这种疾病过程的效率和可重复性，并有效地 比较五个独立项目的结果。 相关性（参见说明）： 创伤动物模型对于哺乳动物创伤生物学研究至关重要。