MT INBRE RESEARCH CORE

MT INBRE 研究核心

• 批准号: 7725983
• 负责人: Timothy Edgcumbe Ford
• 金额: $ 162.72万
• 依托单位: MONTANA STATE UNIVERSITY - BOZEMAN
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7725983
• 关键词: Antifungal Agents; Area; Bioinformatics; Chronic Wasting Disease; Collaborations; Communicable Diseases; Computer Retrieval of Information on Scientific Projects Database; Crows; Data Quality; Docosahexaenoic Acids; Doctor of Medicine; Ecology; Engineering; Environmental Health; Environmental Pollution; Equipment; Funding; Gestational Diabetes; Goals; Grant; Hantavirus; Health; Hospitals; Human Development; Indian reservation; Infection Control; Institution; Laboratories; Link; Location; Mentors; Microbial Biofilms; Molecular Biology; Montana; Organism; Pilot Projects; Positioning Attribute; Pregnant Women; Primary Care Physician; Research; Research Institute; Research Personnel; Research Project Grants; Research Support; Reservations; Resources; Skiing; Source; Technology; Training; United States National Institutes of Health; Work; Yeasts; college; fungal genetics; methicillin resistant Staphylococcus aureus; outreach; programs; transmission process; water quality

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Nine research projects, including the two pilot projects led by Project Leaders Marisa Pedulla and Kurt Toenjes, in the areas of infectious disease and environmental health are supported by the MT INBRE Research Core at four of the state's baccalaureate colleges. (The tenth research project directed by Mari Eggers is supported by the Outreach Core.) Five of the eight projects take advantage of their location in Montana, focusing on the ecology of reservoirs and transmission of hantaviruses, isolating antifungal compounds from unique micro-organisms from the Berkeley Pit in Butte, collecting water quality data to determine environmental contamination on the Crow Indian Reservation (in the Outreach Core), and investigating chronic wasting disease, an emerging problem in the state. Other projects take advantage of cutting edge technologies and expertise at MSU in fungal genetics and in the Center for Biofilm Engineering. An extensive mentoring and research collaboration program links the Project Leaders of each of these projects with established, NIH-funded investigators at MSU-Bozeman, UM-Missoula, the McLaughlin Research Institute, and the NIH Rocky Mountain Laboratories. All network researchers have access to shared facilities, equipment, and training at MSU-Bozeman and UM-Missoula. The long-term goal is to position these researchers to be competitive for their own NIH funding. In addition to these research projects, three research sub-groups have developed and are increasingly visible mechanisms for providing training, collaborations, and research support for the Project Leaders. Included in these groups are the Big Sky Yeast Group, the Bioinformatics Users Group (in the Bioinformatics Core), and the Environmental Health Working Group (in the Outreach Core). Two new pilot projects have been added to the Research Core. The first, led by junior investigator, Dr. Christina Campbell (Department of Health and Human Development, MSU-Bozeman) focuses on DHA Status in Pregnant Women with and without Gestational Diabetes. The second focuses on MRSA on the Apsaalooke Reservation and is co-directed by Dr. Jovanka Voyich-Kane (Department of Veterinary Molecular Biology, MSU-Bozeman) and Dr. David Mark, M.D., Infection Control Officer and primary care physician at the Crow-Northern Cheyenne IHS Hospital in Crow Agency.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 传染病和环境健康领域的九个研究项目，包括由项目负责人 Marisa Pedulla 和 Kurt Toenjes 领导的两个试点项目，得到了该州四所学士学位学院的 MT INBRE 研究核心的支持。 （Mari Eggers 指导的第十个研究项目得到了 Outreach Core 的支持。）八个项目中的五个项目利用了蒙大拿州的地理位置，重点关注水库生态和汉坦病毒的传播，从 Butte 伯克利坑的独特微生物中分离出抗真菌化合物，收集水质数据以确定 Crow Indian Reservation（在 Outreach Core 中）的环境污染，并调查 慢性消耗性疾病是该州一个新出现的问题。其他项目利用了密歇根州立大学真菌遗传学和生物膜工程中心的尖端技术和专业知识。广泛的指导和研究合作计划将每个项目的项目负责人与密歇根州立大学博兹曼分校、密歇根大学密苏拉分校、麦克劳林研究所和 NIH 落基山实验室的 NIH 资助的研究人员联系起来。 所有网络研究人员都可以使用 MSU-Bozeman 和 UM-Missoula 的共享设施、设备和培训。 长期目标是使这些研究人员在获得 NIH 资助时具有竞争力。 除了这些研究项目之外，三个研究小组已经开发并日益成为为项目负责人提供培训、合作和研究支持的机制。 这些小组包括 Big Sky Yeast Group、生物信息学用户组（位于生物信息学核心）和环境健康工作组（位于外展核心）。 研究核心中添加了两个新的试点项目。 第一个项目由初级研究员 Christina Campbell 博士（密歇根州立大学博兹曼分校健康与人类发展系）领导，重点研究患有和不患有妊娠期糖尿病的孕妇的 DHA 状况。 第二个重点是 Apsaalooke 保留地的 MRSA，由 Jovanka Voyich-Kane 博士（MSU-Bozeman 兽医分子生物学系）和 David Mark 博士（Crow Agency 的 Crow-Northern Cheyenne IHS 医院感染控制官员和初级保健医师）共同指导。