MT INBRE RESEARCH CORE

MT INBRE 研究核心

• 批准号: 7960217
• 负责人: Timothy Edgcumbe Ford
• 金额: $ 178.46万
• 依托单位: MONTANA STATE UNIVERSITY - BOZEMAN
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-10 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7960217
• 关键词: Antifungal Agents; Area; Bioinformatics; Chronic Wasting Disease; Collaborations; Communicable Diseases; Computer Retrieval of Information on Scientific Projects Database; Crows; Data; Doctor of Medicine; Ecology; Engineering; Environmental Health; Environmental Pollution; Equipment; Funding; Gestational Diabetes; Goals; Grant; Hantavirus; Health; Hospitals; Human Development; Indian reservation; Infection Control; Institution; Interdisciplinary Study; Laboratories; Link; Location; Mentors; Microbial Biofilms; Molecular Biology; Montana; Organism; Pilot Projects; Positioning Attribute; Pregnant Women; Primary Care Physician; Research; Research Institute; Research Personnel; Research Project Grants; Research Support; Reservations; Resources; Skiing; Source; Technology; Training; United States National Institutes of Health; Yeasts; college; fungal genetics; methicillin resistant Staphylococcus aureus; outreach; programs; transmission process; water quality; working group

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Nine research projects, including the two pilot projects led by Project Leaders Marisa Pedulla and Kurt Toenjes, in the areas of infectious disease and environmental health are supported by the MT INBRE Research Core at four of the state's baccalaureate colleges. (The tenth research project directed by Mari Eggers is supported by the Outreach Core.) Five of the eight projects take advantage of their location in Montana, focusing on the ecology of reservoirs and transmission of hantaviruses, isolating antifungal compounds from unique micro-organisms from the Berkeley Pit in Butte, collecting water quality data to determine environmental contamination on the Crow Indian Reservation (in the Outreach Core), and investigating chronic wasting disease, an emerging problem in the state. Other projects take advantage of cutting edge technologies and expertise at MSU in fungal genetics and in the Center for Biofilm Engineering. An extensive mentoring and research collaboration program links the Project Leaders of each of these projects with established, NIH-funded investigators at MSU-Bozeman, UM-Missoula, the McLaughlin Research Institute, and the NIH Rocky Mountain Laboratories. All network researchers have access to shared facilities, equipment, and training at MSU-Bozeman and UM-Missoula. The long-term goal is to position these researchers to be competitive for their own NIH funding. In addition to these research projects, three research sub-groups have developed and are increasingly visible mechanisms for providing training, collaborations, and research support for the Project Leaders. Included in these groups are the Big Sky Yeast Group, the Bioinformatics Users Group (in the Bioinformatics Core), and the Environmental Health Working Group (in the Outreach Core). Two new pilot projects have been added to the Research Core. The first, led by junior investigator, Dr. Christina Campbell (Department of Health and Human Development, MSU-Bozeman) focuses on DHA Status in Pregnant Women with and without Gestational Diabetes. The second focuses on MRSA on the Apsaalooke Reservation and is co-directed by Dr. Jovanka Voyich-Kane (Department of Veterinary Molecular Biology, MSU-Bozeman) and Dr. David Mark, M.D., Infection Control Officer and primary care physician at the Crow-Northern Cheyenne IHS Hospital in Crow Agency.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 9个研究项目，包括由项目负责人Marisa Pedulla和Kurt Toenjes领导的两个试点项目，在传染病和环境健康领域得到了该州四所本科院校MT INBRE研究核心的支持。(由Mari Eggers指导的第十个研究项目由外联核心提供支持。)八个项目中的五个利用了它们在蒙大拿州的地理位置，重点是水库的生态和汉坦病毒的传播，从巴特的伯克利坑中分离出独特微生物的抗真菌化合物，收集水质数据以确定乌鸦印第安人保护区(在外联核心)的环境污染，并调查慢性消耗性疾病，这是该州正在出现的一个问题。其他项目利用密歇根州立大学真菌遗传学和生物膜工程中心的尖端技术和专业知识。广泛的指导和研究协作计划将每个项目的项目负责人与密歇根州立大学博兹曼分校、密歇根州立大学米苏拉分校、麦克劳克林研究所和NIH落基山实验室的知名研究人员联系起来。所有网络研究人员都可以使用密歇根州立大学博兹曼分校和密苏拉州立大学的共享设施、设备和培训。长期目标是让这些研究人员在他们自己的NIH资金方面具有竞争力。 除了这些研究项目外，还有三个研究小组制定了为项目负责人提供培训、协作和研究支持的机制，而且这种机制越来越明显。这些小组包括大天空酵母小组、生物信息学用户小组(在生物信息学核心中)和环境健康工作组(在外联核心中)。 研究核心增加了两个新的试点项目。第一个由初级研究员Christina Campbell博士(MSU-Bozeman卫生与人类发展部)领导，重点研究患有和不患有妊娠期糖尿病的孕妇的DHA状态。第二个重点是Apsaalooke保护区的MRSA，由Jovanka Voyich-Kane博士(密歇根州立大学博兹曼分校兽医分子生物系)和David Mark博士共同指导，David Mark博士是Crow Agency的Crow-Northern夏延IHS医院的感染控制官员和初级保健医生。