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AGE-ASSOCIATED CHANGES IN MICROGLIAL PHENOTYPE REGULATE RESPONSE TO BETA-AMYLOID

AGE-ASSOCIATED CHANGES IN MICROGLIAL PHENOTYPE REGULATE RESPONSE TO BETA-AMYLOID
与年龄相关的小胶质细胞表型变化调节对β-淀粉样蛋白的反应
批准号：
7720888
负责人：
Colin K Combs
金额：
$3.96万
依托单位：
UNIVERSITY OF NORTH DAKOTA
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-06-01 至 2009-05-31
来源：
https://reporter.nih.gov/project-details/7720888
关键词：
AgeAmyloid beta-ProteinComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantInstitutionPeptidesPhagocytosisPhenotypeResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healthreceptor expressionresponse

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Specific Aim: Determine whether differential receptor expression/function with age is responsible for a change in microglial ability to phagocytose and respond to fibrillar A Beta peptides.
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