LARGE FRAGMENT OF A POLYKETIDE SYNTHASE
LARGE FRAGMENT OF A POLYKETIDE SYNTHASE
批准号:
7722091
负责人:
Adrian Tristan Keatinge-Clay
金额:
$0.04万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-03-01 至 2009-02-28
中文摘要
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
这将是迄今为止已解决的聚酮合酶的最大片段。它将揭示红霉素等药物是如何在自然界中合成的机制。
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This will be the largest fragment of a polyketide synthase that has been solved todate. It will reveal mechanisms of how drugs like erythromycin are synthesized in nature.
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会议论文
Harnessing Polyketide Assembly Lines for Medicinal Chemistry
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批准号:10651828
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项目类别:
-
资助金额:$31.8万
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财政年份:2022
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负责人:Adrian Tristan Keatinge-Clay
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依托单位:
Determining the Architectures and Activities of Polyketide Synthase Modules
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批准号:8483073
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项目类别:
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资助金额:$28.12万
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财政年份:2013
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负责人:Adrian Tristan Keatinge-Clay
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依托单位:
Determining the Architectures and Activities of Polyketide Synthase Modules
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批准号:10669273
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项目类别:
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资助金额:$31.91万
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财政年份:2013
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负责人:Adrian Tristan Keatinge-Clay
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依托单位:
Determining the Architectures and Activities of Polyketide Synthase Modules
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批准号:9918938
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项目类别:
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资助金额:$30.63万
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财政年份:2013
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负责人:Adrian Tristan Keatinge-Clay
-
依托单位:
Determining the Architectures and Activities of Polyketide Synthase Modules
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批准号:9263990
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项目类别:
-
资助金额:$28.12万
-
财政年份:2013
-
负责人:Adrian Tristan Keatinge-Clay
-
依托单位:
Determining the Architectures and Activities of Polyketide Synthase Modules
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批准号:8691933
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项目类别:
-
资助金额:$28.12万
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财政年份:2013
-
负责人:Adrian Tristan Keatinge-Clay
-
依托单位:
Determining the Architectures and Activities of Polyketide Synthase Modules
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批准号:10522700
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项目类别:
-
资助金额:$31.91万
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财政年份:2013
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负责人:Adrian Tristan Keatinge-Clay
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依托单位:
DISSECTING AN ANTIBIOTIC FACTORY: OBTAINING THE STRUCTURE OF A POLYKETIDE SYNTHA
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批准号:7722011
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项目类别:
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资助金额:$0.02万
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财政年份:2008
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负责人:Adrian Tristan Keatinge-Clay
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依托单位:
海外基金