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PROTEIN FUNCTIONAL ANNOTATION

PROTEIN FUNCTIONAL ANNOTATION
蛋白质功能注释
批准号:
7723536
负责人:
MATTHEW P JACOBSON
金额:
$0.58万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-07-01 至 2009-06-30

项目摘要

项目成果

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. An enormous number of proteins have been sequenced and their structure and function have not been correctly characterized. We use homology modeling, docking and molecular-mechanics generalized Born surface area (MM-GBSA) based method to calculate relative binding energy and rank metabolite ligands. These compounds are subsequently tested in the Gerlt's lab at UIUC.
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会议论文
Modeling Project
CORRELATED MOTIONS AND ALLOSTERY
REFINEMENT AND RESCORING THE DOCKING RESULTS
PROTEIN FUNCTIONAL ANNOTATION
国内基金
海外基金
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