COLLABORATORY EXTENSION TO CHIMERA

合作扩展至嵌合体

• 批准号: 7723473
• 负责人: CONRAD C HUANG
• 金额: $ 2.87万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723473
• 关键词: Accounting; Biological Models; Chimera organism; Color; Computer Retrieval of Information on Scientific Projects Database; Computer software; Condition; Country; Development; Distant; Environment; Funding; Grant; Institution; Internet; Laboratories; Location; Modeling; Network-based; Participant; Performance; Protocols documentation; Research; Research Personnel; Resources; Scientist; Source; Speed; Standards of Weights and Measures; Technology; Testing; Time; United States National Institutes of Health; Update; Videoconferences; Videoconferencing; Work; Writing; collaboratory; computer network; computing resources; cost; design; firewall; molecular modeling; trend

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Advances in computer networking technology have reformed many of the practices associated with scientific research. Increases in accessibility to high speed networks, and the decreasing cost of high-performance computing resources have created an environment in which researchers can rapidly disseminate information through various network-based means. In an effort to take advantage of this trend, we have written an extension to the Chimera Molecular Modeling System, that allows researchers at geographically distant locations to conduct a 'shared' molecular modeling session in real time. This software, called a 'Collaboratory' (collaborative laboratory) creates an environment in which every user connected to a 'session' has equal control over the model(s) being viewed, and a change made by any participant to the state of the models (e.g. change in color, representation, orientation) is instantly propogated to the other participants. Thus, a synchronized view of the models is maintained at all times throughout a session. The Collaboratory was designed to work over a standard network connection (using Internet Protocol), and has been tested with multiple participants (point-to-point, and groups of three or more). In conjunction with commercially available videoconferencing products, this software effectively enables a group of scientists, located throughout the country, all working on the same project, to conduct their research in a manner similar to if they were all on the same campus. Collaboratory development in the past year has focused primarily on increasing the stability of the software. Additionally, features have been added to enable the user to account for special network conditions, including the presence of a firewall or router (as can be the case when working across a DSL network connection). The Collaboratory is regularly updated to support the use of new Chimera features during collaborative sessions.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。列出的机构为 中心，但不一定是研究者所在的机构。 计算机网络技术的进步改革了许多与科学研究有关的做法。高速网络可访问性的增加以及高性能计算资源成本的降低创造了一个研究人员可以通过各种基于网络的手段快速传播信息的环境。 为了利用这一趋势，我们已经编写了一个扩展的嵌合体分子建模系统，使研究人员在地理上遥远的位置进行“共享”的分子建模会议在真实的时间。这个软件被称为“协作实验室”（collaborative laboratory），它创建了一个环境，在这个环境中，连接到“会话”的每个用户都可以平等地控制正在查看的模型，并且任何参与者对模型状态所做的更改（例如颜色，表示，方向的更改）都会立即传播给其他参与者。因此，在整个会话中始终保持模型的同步视图。 协作实验室设计为通过标准网络连接（使用Internet协议）工作，并已在多个参与者（点对点和三人或三人以上的小组）中进行了测试。该软件与商用视频会议产品相结合，有效地使全国各地从事同一项目的一组科学家能够以类似于他们在同一校园的方式进行研究。 过去一年的合作实验室开发工作主要侧重于提高软件的稳定性。此外，还添加了一些功能，使用户能够考虑特殊的网络条件，包括防火墙或路由器的存在（在DSL网络连接上工作时可能会出现这种情况）。协作实验室定期更新，以支持在协作会话期间使用新的Chimera功能。