HIGH PERFORMANCE COMPUTING INFRASTRUCTURE FOR THE VIRTUAL CELL

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The infrastructure for VCell (which was deployed from the inception as a distributed, web-based client-server environment), as well as associated online documentation and training material have now been in place for over 9 years. Continuous additions of new features and capabilities to the Virtual Cell platform as well as the growth in the number of VCell users has required a constant increase in the computational resources of the VCell server side housed at the CCAM Computational Facility. Our Computational Facility is currently the largest resource for High Performance Computing at UCHC, and includes enterprise computing support for the software development team and collaborative projects. We host and manage several compute clusters totaling >300 CPUs, a 52-CPU bioinformatics cluster, 2 entry-level 64-bit supercomputers (a 16 CPU/96 GB RAM Itanium2 system an 8 CPU/64 GB RAM Xeon MP system), and an iSCSI SAN with 40+ TB of shared RAID storage capacity. The facilitie's enterprise systems, such as 2 AD domains, 3 class C subnets, 100+ workstations, and 30+ dedicated 32-bit and 64-bit Xeon and Opteron servers servers, provide for web hosting (5 domains, 2 wikis), database hosting and management (Oracle and MySQL), remote access (VPN, FTP, http dropbox), experimental and simulation data storage, code repositories (Envy, ClearCase, SVN), remote backup, shared access control, license management, and a grid computing infrastructure part of OpenScienceGrid.