POLYMAVIRUS IN HUMAN RENAL ALLOGRAFT TISSUE

人肾同种异体移植组织中的多聚病毒

• 批准号: 7723380
• 负责人: PARMJEET S RANDHAWA
• 金额: $ 0.05万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723380
• 关键词: Adult; Allografting; Computer Retrieval of Information on Scientific Projects Database; Disease Progression; Distress; Funding; Genomics; Grant; Human; Immunosuppressive Agents; Institution; Kidney; Kidney Diseases; Kidney Transplantation; Pharmaceutical Preparations; Play; Research; Research Personnel; Resources; Role; Source; Structure; Tissues; Transplant Recipients; United States National Institutes of Health; Viral; Virus; kidney allograft

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Polymavirus is latent in the kidney of up to 50% of healthy adults. In kidney transplant patients maintained on immunosuppressive drugs, reactivation of virus can result in polymovirus allograft nephropathy (PVAN). PVAN is an inadequately studied and distressing condidtion that frequently leads to graft loss. The study being proposed explores the notion that changes in viral genomic structure might play an important role in the initiation and subsequent progression of this disease

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