STRUCTURE/FUNCTION OF A TURMOR VIRUS CHAPERONE

肿瘤病毒伴侣的结构/功能

• 批准号: 7723126
• 负责人: MICHAEL V RILEY
• 金额: $ 0.05万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7723126
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Klebsiella; Molecular Chaperones; Polyomavirus Transforming Antigens; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; Virus; three dimensional structure

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The 3D structure of the N terminus of Polyomavirus tumor antigen, J domain, has been determined by NMR. The interface of its interaction with Hsc70 is now being determined. In another project, sequences from new strains of Klebsiella are being compared to determine what species they belong to.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 多瘤病毒肿瘤抗原J结构域N端的三维结构已通过NMR确定。 目前正在确定其与Hsc 70相互作用的界面。 在另一个项目中，正在比较新的克雷伯氏菌菌株的序列，以确定它们属于哪个物种。