Wearable Organic Electric Film RFID Sensors for Monitoring of Airborne Toxicants

用于监测空气中有毒物质的可穿戴有机电薄膜 RFID 传感器

• 批准号: 7652831
• 负责人: Radislav A Potyrailo
• 金额: $ 90.52万
• 依托单位: GENERAL ELECTRIC GLOBAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7652831
• 关键词: Air; Area; Biological; Calibration; Carbazoles; Charge; Chemicals; Communication; Complex; Consumption; Coupled; Data; Data Analyses; Data Collection; Detection; Development; Electronics; Elements; Environment; Exposure to; Film; Fluorenes; Frequencies; Gases; Home environment; Homo; Humidity; Knowledge; Measurement; Measures; Memory; Methodology; Monitor; Multivariate Analysis; Organic Synthesis; Polymers; Population Heterogeneity; Property; Protocols documentation; Radio; Reader; Reading; Relative (related person); Research; Side; Structure; Swelling; System; Technology; Time; Transducers; Variant; Water; Workplace; base; carbazole; chemical property; computerized data processing; conformational conversion; cost; density; design; digital; driving force; electric impedance; environmental chemical; experience; high throughput screening; innovation; meetings; member; molecular recognition; monitoring device; novel; portability; programs; prototype; public health relevance; response; sensor; skills; success; toxicant; transmission process; vapor; volatile organic compound; water vapor

DESCRIPTION (provided by applicant): Development of wearable sensors for point-of-contact, near-real time monitoring of exposure to environmental chemical species is critical to the success of studies of diverse populations. The demand for these sensors is driv- en by the yet unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption. In the proposed program, GE Global Research team will meet these require- ments for wearable sensors through the development of a new sensing platform that will dramatically decrease the complexity of accurate monitoring of airborne toxicants such as volatile organic compounds as well as re- ducing and oxidizing gases. The proposed sensor system will employ a novel sensing approach recently devel- oped at GE Global Research that utilizes resonant antenna structures of passive inductively coupled radio-fre- quency identification (RFID) sensors with organic electronic films that will serve as analyte-sensing coatings. This new sensing approach will provide selective quantitation of toxic volatile species with sub-ppm detection limits in presence of uncontrolled variations of ambient humidity. This response selectivity will be achieved not with an array of these sensors but with a single sensor. Such capability will be accomplished by capitalizing on (1) molecular recognition of gases by organic electronic polymers using several vapor-response mechanisms that act simultaneously, (2) new design of sensor transducer to fully probe these vapor-polymer interactions, and (3) standard multivariate analysis of the complex impedance response of the resonance sensor antenna structure. Developed sensors will be interrogated by a matchbox-sized, wearable sensor reader that will relate the findings to a local base station for a long-range transmission. The assembled research team has significant and recog- nized practical knowledge in chemical sensor design, synthesis of organic electronic polymers, low-power RF communications, and multivariate signal processing. This expertise will be coupled with key preliminary results that will facilitate the success of the proposed program. PUBLIC HEALTH RELEVANCE: An unmet need for wearable sensors to simultaneously and selectively measure multiple analytes with negligible power consumption is a strong driving force in the development of new sensing concepts. In the proposed pro- gram, the team will employ a novel sensing approach that utilizes resonant antenna structures of passive induc- tively coupled radio-frequency identification (RFID) sensors with organic electronic films that will serve as ana- lyte-sensing coatings. This new sensing approach will provide a wearable, cost-effective, selective sensor for de- tection of toxic volatile species.

描述（由申请人提供）：开发可穿戴传感器，用于接触点，近实时监测环境化学物质的暴露，这对于不同人群研究的成功至关重要。对这些传感器的需求是由尚未满足的可穿戴传感器驱动的，这些传感器可以同时有选择地测量多种分析物，而功耗可以忽略不计。在拟议的项目中，GE全球研究团队将通过开发一种新的传感平台来满足可穿戴传感器的这些要求，该平台将大大降低准确监测空气中有毒物质（如挥发性有机化合物以及还原和氧化气体）的复杂性。提出的传感器系统将采用GE全球研究中心最近开发的一种新型传感方法，该方法利用无源电感耦合射频识别（RFID）传感器的谐振天线结构，有机电子薄膜将作为分析物传感涂层。这种新的传感方法将在环境湿度不受控制的变化存在的情况下，提供有毒挥发性物质的亚ppm检测限的选择性定量。这种响应选择性不是用这些传感器的阵列而是用单个传感器来实现的。这种能力将通过以下几个方面来实现：(1)有机电子聚合物对气体的分子识别，使用几种同时起作用的蒸汽响应机制；(2)传感器传感器的新设计，以充分探测这些蒸汽-聚合物相互作用；(3)共振传感器天线结构的复杂阻抗响应的标准多元分析。开发的传感器将由一个火柴盒大小的可穿戴传感器读取器进行查询，该读取器将发现的数据与本地基站进行远程传输。组建的研究团队在化学传感器设计、有机电子聚合物合成、低功耗射频通信和多元信号处理方面具有重要和公认的实践知识。这种专业知识将与关键的初步结果相结合，这将促进拟议计划的成功。公共卫生相关性：对可穿戴传感器的需求尚未得到满足，可以同时有选择地测量多种分析物，而功耗可以忽略不计，这是开发新传感概念的强大推动力。在该计划中，该团队将采用一种新颖的传感方法，该方法利用无源电感耦合射频识别（RFID）传感器的谐振天线结构，并将有机电子薄膜用作电解质传感涂层。这种新的传感方法将为检测有毒挥发性物质提供一种可穿戴的、经济有效的、选择性的传感器。