Ethical Legal and Social Dimensions of Human Microbiome Research

人类微生物组研究的伦理法律和社会维度

• 批准号: 7743963
• 负责人: Amy L McGuire
• 金额: $ 37.54万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-10 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7743963
• 关键词: Bacteria; Code; Collection; Dimensions; Disease; Educational workshop; Environment; Ethical Analysis; Ethics; Feedback; Female; Funding; Future; Goals; Health; Human; Human Microbiome; Individual; Interview; Investigation; Learning; Life; Medicine; Methods; Organism; Participant; Pattern; Perception; Phase; Recommendation; Recruitment Activity; Research; Research Personnel; Scientist; Surveys; Thinking; United States National Institutes of Health; Virus; base; college; comparative; ethical legal social implication; experience; human subject protection; male; member; microbial; public health relevance; social; sound

DESCRIPTION (provided by applicant): We propose an exploratory survey, parallel to the Human Microbiome Project (HMP), of the emergent ethical, legal, and social issues associated with human microbiome research. We will implement this study using in- depth interviews with key stakeholders in the HMP, including individuals who are recruited to the HMP but decline participation, study participants, and investigators and project leaders involved in planning for an conducting the first phases of the HMP. The overall goal of this project is to identify and analyze ethical, legal, and social issues related to human microbiome research and to develop ethically sound and empirically informed strategies for managing these issues in future research. This project has three Specific Aims: (1) Describe recruits and participants' ideas about the HMP (and participants' experiences of the HMP) as it relates to them physically, socially, and culturally and as it relates to their notions of health and disease, (2) Describe the ethical, legal, and social challenges of conducting the HMP from the perspective of study investigators and project leaders at the NIH, and (3) Provide a forum for interdisciplinary exchange with representative stakeholders (including study participants, members of the research team, and outside experts) to develop recommendations for the responsible management of ethical, legal, and social issues identified in Specific Aims 1 and 2. PUBLIC HEALTH RELEVANCE: The Human Microbiome Project (HMP) is a large study to learn more about the collections of bacteria, viruses and other tiny organisms that live in and on our bodies. We will interview three groups of people: (1) those who are asked to participate in the HMP but say no, in order find out why they said no, (2) those who decide to participate in the HMP, in order to explore their thoughts about the project and their experience with participating in the project, and (3) scientists who are conducting the HMP, in order to understand what ethical or social issues are related to this type of research. We will also host a workshop with members of our research team, study participants, and outside experts to discuss the issues that were identified in the interviews and develop recommendations for managing them.

描述（由申请人提供）：我们提出了一项与人类微生物组研究相关的新兴道德，法律，法律和社会问题，与人类微生物组项目（HMP）平行的探索性调查。我们将使用与HMP中主要利益相关者的深入访谈实施这项研究，包括被招募到HMP但降低参与，研究参与者以及参与计划进行HMP第一阶段的研究人员和项目负责人。该项目的总体目标是识别和分析与人类微生物组研究相关的道德，法律和社会问题，并制定道德上合理的和经验知情的策略，以在未来的研究中管理这些问题。该项目具有三个具体的目的：（1）描述招聘人员和参与者对HMP（以及参与者的HMP经历）的想法，因为它在身体，社会和文化上，文化，文化，以及与他们的健康和疾病的概念有关，与他们的健康和疾病的概念有关，（2）描述了伦理，法律和社会挑战，从研究者和社会挑战中，研究人员和项目的社会挑战（3）是研究人员和计划的研究员（3）研究员（3）研究员（3）研究员（3）。 interdisciplinary exchange with representative stakeholders (including study participants, members of the research team, and outside experts) to develop recommendations for the responsible management of ethical, legal, and social issues identified in Specific Aims 1 and 2. PUBLIC HEALTH RELEVANCE: The Human Microbiome Project (HMP) is a large study to learn more about the collections of bacteria, viruses and other tiny organisms that live in and on our bodies.我们将采访三组人：（1）那些被要求参加HMP的人，但请否，以了解他们为什么拒绝，（2）决定参加HMP的人，以探索他们对项目的想法以及参与该项目的经验，以及（3）正在进行HMP的科学家，以了解与此相关或社交相关的研究，以了解与此相关的研究。我们还将与我们的研究团队，研究参与者和外部专家的成员举办研讨会，讨论访谈中确定的问题，并制定管理人员的建议。