TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 A.具体目标 我们METRC计划的这一部分的目标是建立一个蛋白质组学核心设施，该设施将服务于广泛的研究社区，并将显著加强Meharry医学院的翻译和临床研究。目标包括获得一个用于蛋白质样品的LC-MS/MS分析系统，并为我们的教职员工和受训人员的蛋白质组学教育和推广建立适当的基础设施。这项活动的目的是使研究人员和受训人员能够获得有关他们感兴趣的蛋白质的关键信息，并在基础、临床和翻译环境中促进蛋白质的发现。拟议活动的具体目标是：(1)开发蛋白质组学核心设施，以支持Meharry的临床和翻译研究活动；以及(2)发展Meharry医学院内外的合作和伙伴关系，以加快临床和翻译研究，共同的联系是依赖最先进的蛋白质组学战略。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A. Specific Aims The objective of this component of our MeTRC Program is to establish a Proteomics Core facility, which will serve the broad research community and will significantly enhance translational and clinical research at Meharry Medical College. The goals include acquiring an LC-MS / MS system for mass spectrometry analysis of protein samples, and to establish the appropriate infrastructure for proteomics education and outreach among our faculty and trainees. This activity is aimed to provide researchers and trainees the ability to obtain critical information about their proteins of interest and to advance protein discovery in basic, clinical and translational settings. The specific aims of the proposed activity are: (1) To develop a Proteomics Core Facility to support Meharry's clinical and translational research activities; and (2) To develop collaborations and partnerships inside and outside of Meharry Medical College that accelerate clinical and translational research, with the common link being the reliance on state-of-the-art proteomics strategies.