PSM Moffitt Cancer Center Partnership

PSM 莫菲特癌症中心合作伙伴

• 批准号: 7901640
• 负责人: Jose A Torres-Ruiz
• 金额: $ 40.7万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-20 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7901640
• 关键词: PSM; Moffitt; Cancer; Center; Partnership

The geographic proximity and large Hispanic populations in Florida and Puerto Rico have driven a longstanding effort by the Ponce School of Medicine and the Moffitt Cancer Center to develop an academic partnership. The complementary expertise at both institutions provides a synergistic means of studying the cancer problem in Puerto Ricans, and in the Hispanic population in general. Interactions between the PSM and the MCC have been ongoing for the past 4 years, and effective working relationships between theleadership and investigators from both institutions have been formed, and collaborations have begun. An implementation plan has been devised focusing on four target areas: (1) basic research, (2) cancer education and training, (3) outreach, and (4) tissue procurement. Basic scientists from both institutions with shared interests and complementary expertise have jointly developed 2 basic research projects: (1) "Cutaneous human papillomavirus infection and non-melanoma skin cancer in the U.S. and Puerto Rico," and (2) "Targeting SP-NK1R-EGFR interactions in colitis associated dysplasia" In addition to synergistic hypothesis generation the partnership permits the sharing of technology available at the MCC and not at the PSM, and allows the PSM to develop cancer research programs, utilizing the expertise of MCC faculty. It is also a high priority of the PSM to develop the capacity to conduct investigator-initiated clinical research involving cancer patients, and to recruit new cancer faculty through the RCMI Program to accomplish this. Although the PSM has considerable expertise in other clinical disciplines, oncology needs to be developed in order to serve as a tertiary referral center for cancer care in southwest Puerto Rico. The cancer education and training program is designed to accomplish this in staged fashion. Plans for the training of medical students, residents, and faculty in cancer care and clinical research have been devised. The outreach program will eventually encompass a variety of different cancer prevention activities. Initially, a social marketing strategy will be used to determine the needs in Puerto Rico. The Tissue Procurement Core will support the research projects by banking tissue from cancer patients and normal controls in Puerto Rico. The reciprocal benefits for the MCC are the training of medical students, oncology fellows, and faculty in issues specific to the cancer problem in Puerto Rico that will provide an enhanced ability to appropriately treat Hispanic cancer patients in Florida, more effectively involve them in clinical research, and produce more effective cancer control programs for Hispanic communities in Florida. A partnership between the PSM and the MCC will likely lead to improved outcomes for Hispanic cancer patients in Puerto Rico and Florida who are currently underserved with respect to cancer care and participation in clinical research.

佛罗里达和波多黎各地理上的接近和大量的西班牙裔人口推动了长期的 庞塞医学院和莫菲特癌症中心努力发展学术伙伴关系。这两个机构的互补专业知识为研究波多黎各人和西班牙裔人口的癌症问题提供了一种协同手段。政治和安全委员会与管理协委会之间的互动在过去4年中一直在进行，领导层与两个机构的调查人员之间已经建立了有效的工作关系，合作也已开始。制定了一项实施计划，重点是四个目标领域：（1）基础研究，（2）癌症教育和培训，（3）推广，（4）组织采购。来自两个机构的基础科学家具有共同的兴趣和互补的专业知识，共同开发了2个基础研究项目：（1）“美国和波多黎各的皮肤人乳头瘤病毒感染和非黑色素瘤皮肤癌”， 和（2）“靶向结肠炎相关异型增生中的SP-NK 1 R-EGFR相互作用”除了协同假说的产生，该伙伴关系还允许在MCC而不是PSM共享可用的技术，并允许PSM利用MCC教师的专业知识开发癌症研究计划。PSM的一个高度优先事项是发展开展涉及癌症患者的临床研究的能力，并通过RCMI计划招募新的癌症教师来实现这一目标。虽然PSM在其他临床学科有相当多的专业知识，肿瘤学需要发展，以作为波多黎各西南部癌症护理的三级转诊中心。癌症教育和培训计划旨在分阶段实现这一目标。已经制定了培训医学生、住院医生和癌症护理和临床研究教师的计划。 外展计划最终将包括各种不同的癌症预防活动。最初，将采用社会营销战略来确定波多黎各的需求。组织采购中心将通过储存来自波多黎各癌症患者和正常对照组的组织来支持研究项目。MCC的互惠互利是对医学生、肿瘤学研究员和教职员工进行波多黎各癌症问题方面的培训，这将增强适当治疗佛罗里达西班牙裔癌症患者的能力，更有效地让他们参与临床研究，并为佛罗里达的西班牙裔社区制定更有效的癌症控制计划。PSM和MCC之间的伙伴关系可能会改善波多黎各和佛罗里达的西班牙裔癌症患者的预后，这些患者目前在癌症护理和参与临床研究方面服务不足。