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中文摘要
翻译
行政核心的具体目标和职责是: (1)将MDS患者输入白血病数据库,并确保患者继续接受适当的治疗。 协议; (2)协助核心B进行样品采集,并确保将样品结果发送至实验室 项目2-5的调查人员已汇报; (3)维护当前的FileMan数据库,并协助过渡到新的基于Oracle的数据库 (4)组织计划项目人员会议和内部及外部咨询会议 委员会 (5)协调项目产生的报告和手稿; (6)监控所有项目和核心的支出。 为了登记和随访,我们将使用白血病科的既定程序, MDACC。这些都是由经验丰富的人员监督,并已成为许多出版物的基础。我们 将跟踪各计划项目实验室收到的样品数量与 在MDACC白血病科就诊的MDS患者,以及通过 这些实验室在收到后的两个月内被输入方案项目数据库。现有 白血病数据库包含超过2,000例MDS患者的治疗前、反应和生存数据。 Drs. Estey和Kantarjian将领导行政核心,提供领导和一般管理, 所有与P01相关的活动。
英文摘要
The specific objectives and responsibilities of the Administrative Core are: (1) Enter patients with MDS into the Leukemia Database and ensure that patients go on the appropriate protocols; (2) Assist Core B in sample acquisition and ensure that results from samples sent to laboratory investigators in Projects 2-5 are reported back; (3) Maintain the current FileMan database and facilitate the transition to the new Oracle-based database (4) Organize meetings of Program Project personnel and of Internal and External Advisory Committees (5) Coordinate reports and manuscripts resulting from the Program Project; (6) Monitor expenditures for all Projects and Cores. For purposes of registration and follow-up, we will use established routines in the Leukemia Department at MDACC. These are overseen by experienced personnel and have been the basis for many publications. We will track the number of samples received at the various program project laboratories relative to the number of patients with MDS seen in the Leukemia Department at MDACC, and the number of samples analyzed by these laboratories and entered into the program project database within two months of receipt. The existing leukemia database contains pre-treatment, response, and survival data on over 2,000 patients with MDS. Drs. Estey and Kantarjian will lead the Administrative Core providing leadership and general administration of all activities related to the P01.
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Clinical Trials in AML
New Approaches to the Biology and Treatment of Myelodysplastic Syndromes (MDS)
New Approaches to the Biology and Treatment of Myelodysplastic Syndromes (MDS)
New Approaches to the Biology and Treatment of Myelodysplastic Syndromes (MDS)
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
芹菜素通过AGE-RAGE通路抑制干眼的炎症与氧化应激
  • 批准号:
    82505677
  • 项目类别:
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  • 资助金额:
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  • 批准年份:
    2025
  • 负责人:
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  • 依托单位:
麝香通心滴丸通过干预AGE-RAGE轴调节O-GlcNAc修饰发挥防治DCM作用的药效物质及机制研究
  • 批准号:
    82574874
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2025
  • 负责人:
    刘天华
  • 依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位: