Directed Transport Physics and Muli-Scale Therapy of Colon Cancer Liver Metatasis

结肠癌肝转移的定向传输物理和多尺度治疗

• 批准号: 7797091
• 负责人: MAURO FERRARI
• 金额: $ 90.72万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-23 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7797091
• 关键词: Animal Model; Biocompatible; Biodegradation; Biological; Biological Factors; Biology; Breast; Cells; Coculture Techniques; Collaborations; Colon Carcinoma; Colorectal; Colorectal Cancer; Computer Simulation; Contrast Media; Cytotoxic agent; Development; Disease; Disorder by Site; Drug Delivery Systems; Drug Kinetics; Drug or chemical Tissue Distribution; E-Selectin; Endothelial Cells; Engineering; Evaluation; Experimental Models; Gastrointestinal Diseases; Goals; Gold; Heating; Hepatocyte; Home environment; Human; Image; In Vitro; Integrated Delivery Systems; Kinetics; Kupffer Cells; Lesion; Ligands; Liver; Location; Lung; Malignant Neoplasms; Malignant neoplasm of pancreas; Mediating; Metastatic Neoplasm to the Liver; Methods; Modality; Modeling; Mus; Nanotechnology; Neoplasm Metastasis; Normal tissue morphology; Operative Surgical Procedures; Patients; Phagocytes; Pharmaceutical Preparations; Physics; Play; Primary Neoplasm; Process; Production; Property; Public Health; Role; Scheme; Shapes; Silicon; Staging; Staging System; Surface Properties; Survival Rate; System; Testing; Therapeutic; Therapeutic Agents; Thermal Ablation Therapy; Tissues; Toxic effect; Toxicity Tests; Treatment Efficacy; Tumor Tissue; Tumor-Associated Vasculature; Tyrosine Kinase Inhibitor; angiogenesis; base; biomaterial compatibility; cancer cell; cancer therapy; chemical property; chemotherapeutic agent; cytokine; design; effective therapy; improved; in vivo Model; macrophage; mathematical model; model development; nanocarrier; nanoparticle; nanovector; neovasculature; novel; novel therapeutics; overexpression; particle; physical model; physical property; radiofrequency; treatment effect; tumor; tumor growth; vector