Administrative Core

行政核心(CAdmin)的组织和职能。作为拟议的TCCN的首席研究员，Mauro Ferrari博士是纳米医学和生物医学工程系(NBME)的主席。Ferrari博士同时担任MDACC(终身教授，实验治疗学)、莱斯大学(生物工程)和德克萨斯大学奥斯汀大学(生物医学工程)的教职，并是纳米健康联盟(ANH)的主席。法拉利博士接受过数学、机械工程和医学方面的培训。他在生物医学纳米技术的开发和应用方面是公认的领导者。在他获得的众多奖项中。Ferrari博士是2008年美国国防部CDMRP乳腺癌研究项目创新者奖的获得者。共同领导TCCN作为主要发起人的是MDACC的Anil K.Sood博士，他是妇科肿瘤学和癌症生物学系Blanton-Davis卵巢癌研究项目的教授和主任。他也是MDACC的RNA干扰和非编码RNA中心的主任。索德博士是一位著名的内科科学家，他在使用生物相容纳米颗粒的体内系统siRNA传递方面的研究以及抗血管治疗新方法的开发而闻名。Gabriel Lopez-Berestein博士是第三位首席研究员，目前是MDACC癌症医学部实验治疗学系医学和癌症生物学教授；MDACC PDC执行董事和莱斯大学兼职教授(生物工程)。Lopez-Berestein博士是脂质体治疗和跨肝研究领域公认的专家。TCCN管理核心将由TCCN的其他重要贡献者、MDACC教务长/执行副总裁Raymond DuBois博士提供建议。 Ferrari、Sood和Lopez-Berestein博士将从应用的角度领导TCCN 纳米技术、临床肿瘤学和药物开发的转化工作。他们中的每一个人都拥有进行和领导多学科研究项目的经验，这些项目架起了物理科学与生物医学和临床科学之间的桥梁。由PIS领导的CAdmin将由中心经理Jason Sakamoto博士协助，为与本TCCN相关的所有活动提供领导和一般管理。CADMIN具体负责：1)为TCCN的所有项目和核心资源提供行政支持；2)提供行政支持，以制定和管理试点项目方案(内部试验项目和跨联盟挑战项目)；3)召开TCCN团队会议、咨询委员会会议以及科学会议和研讨会；4)支持TCCN参与NCI癌症纳米技术联盟，并与NCI工作人员沟通；促进和准备TCCN参与NCI评估；5)促进与其他CCNE方案以及其他行政和支持职能部门的沟通，以及6)与其他行政资源(ANH和nBME)对接，并共享参与机构的核心设施。

Organization and Functions of the Administrative Core (CAdmin). As a Principal Investigator of the proposed TCCN, Dr. Mauro Ferrari is Chairman of the Department of Nanomedicine and Biomedical Engineering (nBME). Dr. Ferrari holds concurrent faculty appointments at MDACC (tenured Full Professor, Experimental Therapeutics), Rice University (Bioengineering) and UT Austin (Biomedical Engineering), and is the President of the Alliance for NanoHealth (ANH). Dr. Ferrari is trained in mathematics, mechanical engineering and medicine. He is a recognized leader in the development and applicafion of biomedical nanotechnology. Among many awards he received. Dr. Ferrari is the recipient of the DoD CDMRP Breast Cancer Research Program's Innovator Award in 2008. Co-leading the TCCN as Principal Invesfigator is Dr. Anil K. Sood of MDACC, Professor and Director ofthe Blanton-Davis Ovarian Cancer Research Program in the Departments of Gynecologic Oncology and Cancer Biology. He is also the Director of the Center for RNA Interference and Non-Coding RNA at MDACC. Dr. Sood is a renowned physician scienfist known for his research on the systemic in vivo siRNA delivery using biocompafible nanoparticles and development of novel anti-vascular therapeufic approaches. Dr. Gabriel Lopez-Berestein Is the third Principal Investigator, and is currently Professor of Medicine and Cancer Biology, Department of Experimental Therapeutics, Division of Cancer Medicine, MDACC; Executive Director, PDC at MDACC and Adjunct Professor at Rice University (Bioengineering). Dr. Lopez-Berestein is a widely recognized expert in the field of liposomal therapeufics and in translafional research. TCCN Administrative Core will be advised by Dr. Raymond DuBois, Other Significant Contributor of TCCN and Provost/Executive Vice President of MDACC. Drs. Ferrari, Sood, and Lopez-Berestein will lead the TCCN from the perspecfives of applied nanotechnology, clinical oncology, and translational work for pharmaceutical development, respectively. Each of them has demonstrated experience to conduct and lead mulfidisciplinary research programs that bridge the physical sciences and biomedical and clinical sciences. The CAdmin led by the Pis will be assisted by a Center Manager, Dr. Jason Sakamoto, to provide leadership and general administration for all activities related to this TCCN. In particular, CAdmin is responsible for: 1) providing administrafive support to all projects and core resources of the TCCN, 2) providing administrative support to develop and manage pilot project programs (Internal pilot projects and Trans-Alliance challenge projects), 3) convening TCCN team meetings, advisory committee meetings, as well as scientific conferences and workshops, 4) supporting the participation of the TCCN in the NCI Alliance for Nanotechnology in Cancer and communicate with NCI staff, facilitate and prepare the TCCN participation in NCI evaluafion, 5) facilitafing communication with other CCNE programs, and among other administrafive and supportive funcfions, and 6) interfacing with other administrative resources (ANH and nBME) and shared core facilities in the participating institutions.