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Mechanism of Alcohol-Associated Breast Cancer

Mechanism of Alcohol-Associated Breast Cancer
酒精相关乳腺癌的机制
批准号:
7847276
负责人:
David Heber
金额:
$3.23万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-01 至 2012-08-31
关键词:
AddressAffectAlcohol consumptionAlcoholsAnisomycinAntibodiesBiological AssayBreastBreast Cancer CellCancer PatientCancer cell lineCell Culture TechniquesCell LineCell NucleolusCellsChemicalsCo-ImmunoprecipitationsDNA-Directed RNA PolymeraseDataDevelopmentDiagnosticDietary FactorsDoseEstrogen AntagonistsEstrogen ReceptorsEstrogensEthanolEventGenesGenetic TranscriptionHumanHuman DevelopmentHypertrophyImmunoblot AnalysisIn SituIn VitroLinkMAPK14 geneMCF7 cellMDA MB 231Malignant NeoplasmsMammary NeoplasmsMeasuresMediatingMessenger RNAMitogen Activated Protein Kinase 1Mitogen-Activated Protein KinasesModelingMolecularNeoplasmsNuclear ExtractOncogene DeregulationPathogenesisPathologistPathway interactionsPharmaceutical PreparationsPlayPolymeraseProtein IsoformsProteinsRNA Polymerase IRNA Polymerase IIIReaction TimeReceptor ActivationReceptor CellRegulationRelative (related person)Reporter GenesReverse Transcriptase Polymerase Chain ReactionRibonucleasesRibosomal RNARiskRoleSignal PathwaySignal Transduction PathwayStressTestingTranscription Factor TFIIIBTransfer RNAUV inducedUntranslated RNAalcohol effectalcohol responsecancer cellcancer riskcell growthcell transformationchromatin immunoprecipitationchronic alcohol ingestiondesignextracellular signal-regulated kinase 3in vitro Assayin vivoinhibitor/antagonistinsightmalignant breast neoplasmpromoterprotein protein interactionresearch studyresponsestable cell linestress-activated protein kinase 1transcription factortranscription factor TFIIICtreatment durationtumor

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