INTERNET BASED TOOLS RESOURCE FOR PROTEIN MASS SPECTROMETRY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们继续维护基于互联网的蛋白质质谱生物信息资源。 这些工具可以在通用资源定位器http://www.rockefeller.edu/labheads/chait/tools.php上找到，包括： 深刻 ProFound是一个用于搜索蛋白质序列集合的工具。贝叶斯算法用于根据它们产生肽图的概率对数据库中的蛋白质序列进行排序。 ProteinInfo ProteinInfo是一个用于检索和分析蛋白质序列的工具集。分析工具的功能包括肽图谱、质谱裂解分析、二硫键图谱等。 肽图谱 PeptideMap是一种发现多肽序列修饰的工具。修饰可以影响单个氨基酸（例如磷酸化或氧化）或交联两个氨基酸（例如二硫键或化学交联试剂）。 PepFrag PepFrag是一种用于从与单个串联质谱匹配的序列集合中识别蛋白质的工具。 X！串联 X！Tandem是一种用于从与串联质谱匹配的肽序列集合中识别蛋白质的工具。 X！猎人 X！Hunter是一种用于识别蛋白质的工具，该蛋白质将串联质谱与已确信分配给特定肽序列的光谱库相匹配。 GPMDB GPMDB是串联质谱及其指定肽序列的数据库。它旨在帮助验证肽MS/MS光谱的困难过程。 NCBI菌株数据库 美国国家动态相互作用组研究中心（NCBI）菌株数据库

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We continue to maintain an internet based bioinformatic resource for protein mass spectrometry. These tools ca be found at the universal resource locator http://www.rockefeller.edu/labheads/chait/tools.php and include: ProFound ProFound is a tool for searching a protein sequence collections with peptide mass maps. A Bayesian algorithm is used to rank the protein sequences in the database according to their probability of producing the peptide map. ProteinInfo ProteinInfo is a collection of tools for retrieval and analysis of protein sequences. The capabilities of the analysis tools include peptide mapping, mass spectrometric fragmentation analysis, disulfide mapping, etc. PeptideMap PeptideMap is a tool for finding modifications on polypeptide sequences. The modifications can be affecting single amino acids (e.g. phoshorylation or oxidation) or cross-linking two amino acids (e.g. disulfide bonds or chemical cross-linking reagents). PepFrag PepFrag is a tool for identifying proteins from a collection of sequences that matches a single tandem mass spectrum. X! Tandem X! Tandem is a tool for identifying proteins from a collection of peptide sequences that matches tandem mass spectra. X! Hunter X! Hunter is a tool for identifying proteins that matches tandem mass spectra to a library of spectra that have been confidently assigned to a particular peptide sequence. GPMDB GPMDB is a database of tandem mass spectra and their assigned peptide sequences. It is designed to aid in the difficult process of validating peptide MS/MS spectra. NCDIR Strain Database The National Center for Dynamic Interactome Research (NCDIR) Strain Database