MAINTENANCE OF MASS SPECTROMETERS & LAB INSTRUMENTATION

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。次级项目的主要支助 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 为子项目列出的总成本可能 代表子项目使用的中心基础设施的估计数量， NCRR赠款不直接向子项目或子项目工作人员提供资金。 对1.透视STR反射MALDI飞行时间质谱仪 2. Thermo-Finnigan LTQ电喷雾电离离子阱质谱仪，配有在线HPLC和ETD裂解装置。 3.配备真空MALDI离子源的Thermo-Finnigan LTQ离子阱质谱仪。 注4。Finnigan LCQ-DECA-XP电喷雾电离离子阱质谱仪，配有内部构建的MALDI离子源，并包含我们的CD进样系统。 5. Finnigan LCQ-DECA电喷雾电离离子阱质谱仪，配有在线微流HPLC分离装置。 6.沃茨Synapt离子迁移率四极杆飞行时间质谱仪 注7。原型新型高容量离子阱-四极杆串联质谱仪，安装在原型Sciex QQTOF质谱仪上，该质谱仪配有内部构建的MALDI离子源，并包含我们的自动CD样品入口系统。 8. Perkin Elmer ProTOF正交注入质谱仪 9. Finnigan ETD-LTQ-Orbitrap质谱仪 10. Pharmacia-Amersham Smart HPLC系统 11. LC Packings HPLC系统 12. Micro-Tech Scientific XtremeSimple HPLC系统。 13两个Agilent HPLC系统 质谱仪的服务包括真空泵的维护、离子源的清洁、离子检测器的更换、电子设备的维修; HPLC系统需要活塞泵和注射泵的维护以及密封件、止回阀的更换和故障排除。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Instrument maintenance performed on the 1. Perseptive STR reflectron MALDI time-of-flight mass spectrometer 2. Thermo-Finnigan LTQ electrospray ionization ion trap mass spectrometer fitted with on-line HPLC, and ETD fragmentation facility. 3. Thermo-Finnigan LTQ ion trap mass spectrometer fitted with a vacuum MALDI ion source. *4. Finnigan LCQ-DECA-XP electrospray ionization ion trap mass spectrometer fitted with an in-house constructed MALDI ion source incorporating our CD sample inlet system. 5. Finnigan LCQ-DECA electrospray ionization ion trap mass spectrometer fitted with an on-line microflow HPLC separation unit. 6. Waters Synapt Ion mobility Quadrupole Time-of-Flight Mass Spectrometer *7. Prototype novel high-capacity ion trap-quadrupole tandem mass spectrometer fitted to a prototype Sciex QQTOF mass spectrometer fitted with an in-house constructed MALDI ion source incorporating our automated CD sample inlet system. 8. Perkin Elmer ProTOF orthogonal Injection Mass Spectrometer 9. Finnigan ETD-LTQ-Orbitrap Mass Spectrometer 10. Pharmacia-Amersham Smart HPLC system 11. LC Packings HPLC system 12. Micro-Tech Scientific XtremeSimple HPLC system. 13 Two Agilent HPLC systems Service in the mass spectrometers included maintenance of vacuum pumps, cleaning of the ion source, replacement of ion detectors, repair of electronics; the HPLC systems required maintenance of piston and syringe pumps and replacement of seals, check valves, and trouble shooting.