INTERNET BASED TOOLS RESOURCE FOR PROTEIN MASS SPECTROMETRY
基于互联网的蛋白质质谱工具资源
基本信息
- 批准号:8169103
- 负责人:
- 金额:$ 0.93万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-03-01 至 2011-02-28
- 项目状态:已结题
- 来源:
- 关键词:AffectAlgorithmsAmino Acid SequenceAmino AcidsBioinformaticsChemicalsCollectionComputational BiologyComputer Retrieval of Information on Scientific Projects DatabaseCross-Linking ReagentsDatabasesDisulfidesFundingGrantInstitutionInternetLibrariesManuscriptsMapsMass Spectrum AnalysisMethodsModificationMolecular BiologyPeptide MappingPeptide Sequence DeterminationPeptidesProbabilityProcessProtein Sequence AnalysisProteinsProteomeResearchResearch PersonnelResourcesRetrievalSourceUnited States National Institutes of Healthbasecrosslinkdesigndisulfide bondoxidationpolypeptideprotein aminoacid sequencetool
项目摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
We continue to maintain an internet based bioinformatic resource for protein mass spectrometry. These tools ca be found at the universal resource locator http://www.rockefeller.edu/labheads/chait/tools.php and include:
ProFound
ProFound is a tool for searching a protein sequence collections with peptide mass maps. A Bayesian algorithm is used to rank the protein sequences in the database according to their probability of producing the peptide map.
ProteinInfo
ProteinInfo is a collection of tools for retrieval and analysis of protein sequences. The capabilities of the analysis tools include peptide mapping, mass spectrometric fragmentation analysis, disulfide mapping, etc.
PeptideMap
PeptideMap is a tool for finding modifications on polypeptide sequences. The modifications can be affecting single amino acids (e.g. phoshorylation or oxidation) or cross-linking two amino acids (e.g. disulfide bonds or chemical cross-linking reagents).
PepFrag
PepFrag is a tool for identifying proteins from a collection of sequences that matches a single tandem mass spectrum.
X! Tandem
X! Tandem is a tool for identifying proteins from a collection of peptide sequences that matches tandem mass spectra.
X! Hunter
X! Hunter is a tool for identifying proteins that matches tandem mass spectra to a library of spectra that have been confidently assigned to a particular peptide
sequence.
GPMDB
GPMDB is a database of tandem mass spectra and their assigned peptide sequences. It is designed to aid in the difficult process of validating peptide MS/MS spectra.
(A manuscript describing the Global Protein Macine is in press: D. Feny¿, J. Eriksson and R.C. Beavis, "Mass Spectrometric Protein Identification Using the Global Proteome Machine", Methods in Molecular Biology, Computational Biology, Ed. D. Feny¿, Humana Press, Totowa, NJ, in press 2010.)
NCDIR Strain Database
The National Center for Dynamic Interactome Research (NCDIR) Strain Database
这个子项目是许多研究子项目中利用
资源由NIH/NCRR资助的中心拨款提供。子项目和
调查员(PI)可能从NIH的另一个来源获得了主要资金,
并因此可以在其他清晰的条目中表示。列出的机构是
该中心不一定是调查人员的机构。
我们继续维护基于互联网的蛋白质质谱学生物信息资源。这些工具可在统一资源定位器http://www.rockefeller.edu/labheads/chait/tools.php上找到,包括:
深刻
EPERVER是一个用多肽质量图搜索蛋白质序列集合的工具。贝叶斯算法被用来根据它们产生肽图的概率来对数据库中的蛋白质序列进行排序。
ProteinInfo
ProteinInfo是一组用于检索和分析蛋白质序列的工具。分析工具的功能包括肽图谱、质谱碎片分析、二硫键图谱等。
多肽映射
PeptideMap是一种用于查找多肽序列修饰的工具。修饰可以影响单一氨基酸(例如光短化或氧化)或两个氨基酸的交联性(例如二硫键或化学交联剂)。
PepFrag
PepFrag是一种工具,用于从与单个串联质谱图匹配的一组序列中识别蛋白质。
X!串列
X!Tandem是一种工具,用于从与Tandem质谱图匹配的一组肽序列中识别蛋白质。
X!猎人
X!Hunter是一种用于识别蛋白质的工具,该工具将串联质谱库与已被确定为特定多肽的谱库相匹配
序列。
GPMDB
GPMDB是串联质谱库及其指定的多肽序列的数据库。它的设计是为了帮助验证多肽MS/MS光谱的困难过程。
(描述Global Proteome Macine的手稿正在印刷中:D.Feny?,J.Eriksson和R.C.Beavis,“使用Global Proteome Machine的质谱学蛋白质鉴定”,分子生物学方法,计算生物学,ED。D.Feny?,Humana Press,新泽西州托托瓦,2010年出版。)
NCDIR菌株数据库
国家动态相互作用组研究中心(NCDIR)株系数据库
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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JULIO C PADOVAN其他文献
JULIO C PADOVAN的其他文献
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{{ truncateString('JULIO C PADOVAN', 18)}}的其他基金
INSTALLATION OF PROGRAMS & MAINTENANCE OF COMPUTER RESOURCES
程序安装
- 批准号:
8361550 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
MAINTENANCE OF MASS SPECTROMETERS & LAB INSTRUMENTATION
质谱仪的维护
- 批准号:
8361487 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
INTERNET BASED TOOLS RESOURCE FOR PROTEIN MASS SPECTROMETRY
基于互联网的蛋白质质谱工具资源
- 批准号:
8361488 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
TRAINING OF BIOMEDICAL SCIENTISTS IN MASS SPECTROMETRY
生物医学科学家质谱培训
- 批准号:
8361493 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
SOFTWARE UPGRADES AND MAINTENANCE OF MS INSTRUMENTATION
MS 仪器的软件升级和维护
- 批准号:
8361495 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
TUTORING UNDERGRADUATES IN BIOLOGICAL MASS SPECTROMETRY
辅导本科生生物质谱学
- 批准号:
8361553 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
REORGANIZATION OF THE PHYSICAL MASS SPECTROMETRY LABORATORY
物理质谱实验室的重组
- 批准号:
8361530 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
SOFTWARE CONVERTS RAW-TYPE FILES INTO DTA? AND MGF?FILES FOR DATABASE SEARCH
软件将 RAW 类型文件转换为 DTA?
- 批准号:
8361549 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
INSTALLATION/MAINTENANCE OF GENOMIC, PROTEIN & MS DATABASES
基因组、蛋白质的安装/维护
- 批准号:
8361494 - 财政年份:2011
- 资助金额:
$ 0.93万 - 项目类别:
SOFTWARE CONVERTS RAW-TYPE FILES INTO DTA? AND MGF?FILES FOR DATABASE SEARCH
软件将 RAW 类型文件转换为 DTA?
- 批准号:
8169178 - 财政年份:2010
- 资助金额:
$ 0.93万 - 项目类别:
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