CORE 3: INFRASTRUCTURE

Simtk.org已成为生物医学研究中与基于物理的模拟相关的工具的传播中心，拥有380多个项目和8000多个用户。我们的未来计划是由simtk.org用户数量的快速增长以及我们从他们那里收到的反馈所推动的。在接下来的四年里，我们将建立simtk.org的能力，为众多用户提供可持续的支持模式。我们改进支持的计划是基于社交网络的同行支持和虚拟机的研究结果复制。社交网络（如Facebook）的迅速扩张是自2004年NCBC计划开始以来的一个重要发展。我们的一些软件应用程序拥有大量想要相互交互和支持的用户。因此，我们计划实施基于社交网络范例的工具，以实现同行支持。虚拟机的开发为simtk.org的用户提供了复制他人结果的机会。虚拟机提供了一种机制，用于将操作系统、可执行代码和数据集预加载为表示全功能机器的“映像”的二进制格式。我们的试点研究已经证明了交付二进制文件、文档、模型 和完整的模拟轨迹因此，在未来，我们将提高仿真科学家的能力，以充分详细地分享他们的工作。

Simtk.org has become a hub for the dissemination of tools related to physics-based simulation in biomedical research, with more than 380 projects and 8000 users. Our future plans are driven by this rapid growth in the number of users of simtk.org, and the feedback we receive from them. Over the next four years, we will build the capabilities of simtk.org to create a sustainable model for support for its many users. Our plan for improved support is based on social networking for peer-support and virtual machines for replication of research results. The rapid expansion of social networks, such as Facebook, is an important development since the NCBC program began in 2004. Some of our software applications have a critical mass of users who want to interact and support one another. Thus, we plan to implement tools based on social networking paradigms to enable peer support. The development of virtual machines provides an opportunity for users of simtk.org to reproduce the results of others. Virtual machines provide a mechanism for an operating system, executable codes, and data sets to be pre-loaded into a binary format that represents an "image" of a fully functional machine. Our pilot studies have demonstrated the ability to deliver binaries, documentation, models and full simulation trajectories. Thus, going forward, we will improve the ability of simulation scientists to share their work in full detail.