Biostatistics

生物统计核心设施为以下方面提供统计咨询、分析和数据管理支持 Uno乳腺癌孢子调查员。孢子核心被北卡罗来纳州大学的莱恩伯格扩展 综合癌症中心的生物统计和数据管理核心。孢子核心提供研究 设计、采样、数据管理、分析和稿件准备。数据管理活动 包括：数据库设计、实施、文档编制、维护和用户支持。统计 支持包括：实施和规划具体的抽样方案，协助临床 制定协议，选择适当的设计和统计分析方法，并制定 用于处理非标准情况的特殊软件程序或宏。 孢子公司的生物统计核心得益于对生物统计和数据管理的大量投资 由北卡罗来纳大学莱恩伯格综合癌症中心制作。癌症中心的生物统计和数据 管理核心最近被续签，年度预算为37万美元的CCSG基金，包括 5名教员、4名全职生物统计员和2名研究生研究的部分工资支持 助理。癌症中心核心由约瑟夫·易卜拉欣博士领导，他是麻省理工学院 北卡罗来纳大学公共卫生学院的生物统计学。除了提供统计咨询外， 孢子，易卜拉欣博士将与卡齐什博士合作，确保所有孢子项目都由适当的 反应迅速的教职员工。 这个乳孢子生物统计核心资源远远不止是一个服务核心。这是一条通往卓越的管道 密切参与开发、规划、数据获取、 算法，以及孢子研究的分析。我们的孢子专注于大型数据集，例如 在超过4000名患者和对照组中进行基因分型、微阵列和体细胞突变 为生物统计方法的发展提供了一个很好的场所。在我们的孢子里， 生物统计学家是实验过程中不可或缺的一部分。 为这个核心申请的预算将为专门用于孢子的时间提供少量的工资 以及未来的发展领域。在北卡罗来纳州大学拥有顶级的生物统计和统计部门 校园，孢子和癌症中心生物统计核心都有丰富的教职员工池，可以与之合作 工作和指导临床医生、遗传学家和生物学家。反过来，我们的生物统计学家/统计学家又获得了一流的 有机会分析大型、重要的数据集。

The Biostatistics Core Facility provides statistical consultation, analysis and data management support to UNO Breast Cancer SPORE investigators. The SPORE Core is extended by the UNC Lineberger Comprehensive Cancer Center's Biostatistics and Data Management Core. The SPORE Core offers study design, sampling, data management, analysis, and manuscript preparation. Data management activities include: database design, implementation, documentation, maintenance and user support. Statistical support includes: implementation and programming of specific sampling schemes, assistance in clinical protocol preparation, and choice of proper design and statistical analysis methods and development of special software programs or macros for handling non-standard situations. The SPORE's Biostatistics Core benefits from substantial investments in biostatistics and data management made by the UNC Lineberger Comprehensive Cancer Center. The Cancer Center's Biostatistics and Data Management Core was recently renewed with an annual budget of $370,000 in CCSG funds that includes partial salary support for five faculty members, four full time biostatisticians, and two graduate research assistants. The Cancer Center Core is led by Dr. Joseph Ibrahim, Alumni Distinguished Professor of Biostatistics in UNC's School of Public Health. In addition to providing statistical consultation for the SPORE, Dr. Ibrahim will work with Dr. Qaqish to ensure all SPORE projects are handled by the appropriate faculty and staff with rapid response. This Breast SPORE Biostatistics Core resource is much more than a service core. It is a conduit to superb biostatisticians and programmers who are intimately involved with development, planning, data acquisition, algorithms, and analysis of SPORE studies. Our SPORE's concentration on large data sets, such as genotyping, microarray, and somatic mutation in groups of patients and controls exceeding 4,000 has provided an outstanding venue for the development of biostatistical methods. In our SPORE, the biostatisticians are an integral part of the experimental process. The budget requested for this core will provide a small amount of salary for time dedicated to the SPORE and future areas for development. With top-ranked Departments of Biostatistics and Statistics on the UNC campus, both the SPORE and Cancer Center Biostatistics Cores have a rich pool of faculty with whom to work and direct clinicians, geneticists and biologists. Our biostatisticians/statisticians, in turn, gain a superb opportunity to analyze large, important data sets.