Biostatistics

生物统计学

• 批准号: 7663921
• 负责人: BAHJAT F QAQISH
• 金额: $ 11.56万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7663921
• 关键词: Algorithms; Area; Biometry; Biostatistical Methods; Biostatistics Core; Breast; Budgets; Cancer Center; Cancer Center Support Grant; Clinical Protocols; Computer software; Consultations; Core Facility; Data Analyses; Data Set; Development; Development Plans; Documentation; Ensure; Faculty; Funding; Future; Genotype; Investments; Maintenance; Manuscripts; Patients; Preparation; Process; Public Health Schools; Reproduction spores; Research; Research Design; Research Personnel; Resources; Sampling; Scheme; Services; Somatic Mutation; Standards of Weights and Measures; Time; UNC Lineberger Comprehensive Cancer Center; Wages; Work; data acquisition; data management; database design; design; malignant breast neoplasm; member; method development; professor; programs; response; statistics

The Biostatistics Core Facility provides statistical consultation, analysis and data management support to UNO Breast Cancer SPORE investigators. The SPORE Core is extended by the UNC Lineberger Comprehensive Cancer Center's Biostatistics and Data Management Core. The SPORE Core offers study design, sampling, data management, analysis, and manuscript preparation. Data management activities include: database design, implementation, documentation, maintenance and user support. Statistical support includes: implementation and programming of specific sampling schemes, assistance in clinical protocol preparation, and choice of proper design and statistical analysis methods and development of special software programs or macros for handling non-standard situations. The SPORE's Biostatistics Core benefits from substantial investments in biostatistics and data management made by the UNC Lineberger Comprehensive Cancer Center. The Cancer Center's Biostatistics and Data Management Core was recently renewed with an annual budget of $370,000 in CCSG funds that includes partial salary support for five faculty members, four full time biostatisticians, and two graduate research assistants. The Cancer Center Core is led by Dr. Joseph Ibrahim, Alumni Distinguished Professor of Biostatistics in UNC's School of Public Health. In addition to providing statistical consultation for the SPORE, Dr. Ibrahim will work with Dr. Qaqish to ensure all SPORE projects are handled by the appropriate faculty and staff with rapid response. This Breast SPORE Biostatistics Core resource is much more than a service core. It is a conduit to superb biostatisticians and programmers who are intimately involved with development, planning, data acquisition, algorithms, and analysis of SPORE studies. Our SPORE's concentration on large data sets, such as genotyping, microarray, and somatic mutation in groups of patients and controls exceeding 4,000 has provided an outstanding venue for the development of biostatistical methods. In our SPORE, the biostatisticians are an integral part of the experimental process. The budget requested for this core will provide a small amount of salary for time dedicated to the SPORE and future areas for development. With top-ranked Departments of Biostatistics and Statistics on the UNC campus, both the SPORE and Cancer Center Biostatistics Cores have a rich pool of faculty with whom to work and direct clinicians, geneticists and biologists. Our biostatisticians/statisticians, in turn, gain a superb opportunity to analyze large, important data sets.

生物统计核心基金提供统计咨询、分析和数据管理支持， UNO乳腺癌孢子研究人员。SPORE Core由Lineberger公司的 综合癌症中心的生物统计学和数据管理核心。SPORE Core提供研究 设计、取样、数据管理、分析和手稿准备。数据管理活动 包括：数据库设计、执行、文件编制、维持和用户支助。统计 支持包括：具体抽样计划的实施和规划， 方案准备，选择适当的设计和统计分析方法， 用于处理非标准情况的特殊软件程序或宏。 SPORE的生物统计核心受益于生物统计和数据管理方面的大量投资 这是一份由莱恩伯格综合癌症中心制作的报告。癌症中心的生物统计学和数据 管理核心最近更新了CCSG资金中370，000美元的年度预算，其中包括 部分工资支持五名教员，四名全职生物统计学家，和两名研究生 助手癌症中心核心是由约瑟夫·易卜拉欣博士，校友杰出教授， 公共卫生学院的生物统计学。除了提供统计咨询外， 易卜拉欣博士将与Qaqish博士合作，确保所有SPORE项目都由适当的 教师和工作人员快速反应。 这个Breast SPORE生物统计学核心资源不仅仅是一个服务核心。这是一个管道， 生物统计学家和程序员密切参与开发，规划，数据采集， 算法和SPORE研究的分析。我们的SPORE专注于大型数据集，例如 基因分型、微阵列和超过4,000例患者和对照组的体细胞突变， 为生物统计方法的发展提供了一个出色的场所。在我们的SPORE中， 生物统计学家是实验过程的一个组成部分。 此核心的预算要求将为专门用于SPORE的时间提供少量工资 未来的发展领域。生物统计学和统计学的顶级部门在世界银行 校园，无论是孢子和癌症中心生物统计核心有丰富的教师与谁池， 指导临床医生、遗传学家和生物学家。我们的生物统计学家/统计学家，反过来， 分析大型、重要数据集的机会。