Core A: Administrative Core

行政核心的首要目标是促进、组织和便利 形成中心的跨学科研究和核心活动。项目总监/负责人 Invesfigator将以最佳方式提供领导、监督和组织控制 团队的才能和技能，以实现四个规划目标：1)在以下方面提供领导力和创新 基础和临床研究，加深我们对环境应激源及其对 胎儿发育，2)扩大跨学科研究，拓宽我们对健康风险的理解 与发育相关的暴露和与之相关的潜在分子机制 疾病，3)建立跨领域的桥梁，创造新的跨学科研究、培训和指导 提供机会，以及4)有效地传达潜在的健康危害并将基础研究转化为 为公众健康造福的调查结果。 行政核心将通过发展组织机构来发挥项目的枢纽作用 为形成中心成员之间的沟通建立结构和机制， 临床医生、研究人员、公众、NIEHS工作人员和其他儿童环境组织 健康中心和前五个中心。负责任的财政和资源管理将是首要的 主要发起人的职责，由项目经理协助。行政五核心将 追求以下具体目标： ？具体目标1：提供、支持和开发维持和适应 跨学科基础和应用研究与培训的增长。 ？具体目标2：保持一个加强团队建设和 促进信息的传播。 ？具体目标3：实施以最佳方式促进方案目标的机制 并确保以最佳和最负责任的方式使用现有资源。

The primary objecfive of the Administrative Core is to promote, organize and facilitate the interdisciplinary research and core acfivities of the Formative Center. The Program Director/Principal Invesfigator will provide leadership, supervision and organizafional control in a manner that best ufilizes the team's talents and skills towards four programmafic objectives: 1) provide leadership and innovafion in basic and clinical research that furthers our understanding of environmental stressors and their impact on fetal development, 2) expand interdisciplinary research that broadens our understanding of the health risks associated with developmental exposures and the underiying molecular mechanisms associated with disease, 3) build bridges across fields and create new interdisciplinary research, training, and mentoring opportunifies, and 4) effectively communicate the potential health hazards and translate the basic research findings for the benefit of public health. The Administrative Core will funcfion as the hub of the program by developing the organizational structure and creating mechanisms for communication among the members of the Formative Center, with clinicians, with researchers, with the public, with NIEHS staff, and with other Children's Environmental Health Centers and Formafive Centers. Responsible fiscal and resource management will be the primary responsibility of the Principal Invesfigator, aided by the Program Manager. The Administrafive Core will pursue these Specific Aims: ¿ SpecificAim 1: Provide, support and develop processes that sustain and accommodate the growth of interdisciplinary basic and applied research and training. ¿ Specific Aim 2: Maintain a communication structure that strengthens team building and facilitates the dissemination of information. ¿ Specific Aim 3: Implement mechanisms that will optimally promote the program's objectives and ensure the best and most responsible use of the available resources.