ctsa infrastructure for clinical trials

ctsa 临床试验基础设施

• 批准号: 8175541
• 负责人: ROBERT A. RIZZA
• 金额: $ 338.51万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8175541
• 关键词: Acquired Immunodeficiency Syndrome; Area; Caring; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; Communities; Data; Education; Elements; Ensure; Evaluation; Funding; Goals; Grant; Home environment; Industry; Medical Research; Medicine; Methods; Mission; National Center for Research Resources; Patient Care; Patients; Pediatric Research; Privacy; Regulatory Affairs; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Schools; Services; Site; Speed; Translating; Translational Research; United States National Institutes of Health; Vision; career development; clinical practice; college; cost; empowered; innovation; meetings; member; next generation; patient safety; programs; tool

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of the Mayo Clinic CTSA application is to present our vision for the integration and expansion of our innovative clinical and translational research activities, so that a highly functional academic home for clinical and translational research is developed at the Mayo Clinic. This new Center for Clinical and Translational Research (CCTR) will be founded on Mayo's long-standing excellence in and commitment to clinical and translational research, which includes the support of key infrastructure and a commitment to career development. To achieve this goal we describe a comprehensive approach to the key elements of the CTSA RFA and focus on enhancing: 1) Clinical Research Core Resources that provide innovative tools to investigators; 2) Career Development and Education Programs that prepare the next generation of investigators; 3) Compliance and Regulatory Affairs Support that ensures patient safety and privacy, and customer service-oriented approaches to support investigative teams; 4) Community Affairs support to enhance participation, diversity and community support for clinical and translational research; 5) Collaboration with Industry and Clinical Practices to translate research discoveries into routine clinical practice; and 6) Continued and Expanded Institutional Support that includes an "academic home" for clinical and translational research. We also propose a consolidated governance plan that incorporates strong data-driven evaluation of each CCTR element and the program as a whole. In principle, the CTSA program is consistent with the historical, conceptual and philosophical underpinnings of Mayo Clinic, and in this application we clearly articulate our vision of how the overarching and transformative goals of the CTSA program can be met at Mayo. Additionally, we have the "institutional will" and are culturally empowered to execute our plan. Thus, Mayo is ready to implement the CTSA program aggressively and rapidly; the Mayo Clinic CCTR will be a highly functional and successful "flagship" site for the CTSA program as it emerges from the NIH Roadmap. To summarize, the Mayo Clinic Center for Clinical and Translational Research (CCTR) will bring together all the resources of the five schools within the Mayo Clinic College of Medicine, and more than 100 years of scientific and medical research expertise, to discover innovative new methods that will speed the translation of research results into therapies, tools and patient care practices that impact all members of our local and national communities. This vision is entirely consistent with the stated mission of the Mayo Clinic to provide the best care to every patient every day.through integrated clinical practice, education and research.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 马约诊所CTSA申请的目标是展示我们对创新临床和转化研究活动的整合和扩展的愿景，以便在马约诊所为临床和转化研究开发一个功能齐全的学术之家。这个新的临床和转化研究中心（CCTR）将建立在马约长期以来在临床和转化研究方面的卓越表现和承诺的基础上，其中包括关键基础设施的支持和对职业发展的承诺。为了实现这一目标，我们描述了一个全面的方法的关键要素的CTSA 外地住房储备金和重点加强：1）临床研究核心资源，为研究者提供创新工具; 2）职业发展和教育计划，为下一代研究者做好准备; 3）合规和法规事务支持，确保患者安全和隐私，以及以客户服务为导向的方法，为研究团队提供支持; 4）社区事务支持， 加强临床和转化研究的参与度、多样性和社区支持; 5）与行业和临床实践合作，将研究发现转化为常规临床实践; 6）持续和扩大机构支持，包括临床和转化研究的“学术之家”。我们还提出了一个综合治理计划， 对每个CCTR元素和整个计划进行数据驱动的评估。原则上，CTSA计划与马约诊所的历史、概念和哲学基础一致，在本申请中，我们明确阐述了我们对CTSA总体和变革目标的愿景 可以在马约见面。此外，我们有“机构意愿”，并在文化上有能力执行我们的计划。因此，马约准备积极而迅速地实施CTSA计划;随着CTSA计划的出现，马约诊所的CCTR将成为一个功能强大、成功的“旗舰”网站 NIH路线图。总而言之，马约诊所临床和转化研究中心（CCTR）将汇集马约诊所医学院内五所学校的所有资源，以及100多年的科学和医学研究专业知识，以发现创新的新方法，加快将研究成果转化为治疗方法，工具和病人护理实践，影响我们的地方和国家社区的所有成员。这一愿景完全符合马约诊所的既定使命，即通过综合临床实践、教育和研究，每天为每位患者提供最好的护理。