CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

该子项目代表了 CTSA 资金百分比的估计 被用于广泛的研究领域（艾滋病研究、儿科研究或 临床试验）。 列出的总成本只是 CTSA 金额的估计值 该研究领域的基础设施，而不是直接资助 NCRR 向子项目或子项目人员提供的补助金。 密歇根大学临床和转化科学奖 (UM CTSA) 将集中世界上最好的研究机构之一的强大优势，支持和促进临床和转化“团队科学”。 UM CTSA 将设在新成立的密歇根临床与健康研究所 (MICHR) 内。 MICHR 是由该大学创建的，旨在最大限度地发挥该机构的潜力，该机构大力支持跨学科研究，并在健康科学领域拥有巨大优势。 MICHR 在大学相关单位、NIH、外部行业合作伙伴和社区之间建立了合作伙伴关系。绝大多数密西根大学的学校、学院和研究所都参加了，包括顶尖的商学院、牙科学院、医学院、护理学院、社会工作学院和公共卫生学院、工程学院、药学院、文学、科学和艺术学院、运动机能学部、社会研究所和生命科学研究所。大学拥有的医疗系统包括综合门诊和住院设施，为与 UM CTSA 的牢固合作伙伴关系做出了重大贡献。 MICHR 主任是 UM CTSA 拨款的 PI，并向大学执行副校长报告，后者还负责监督医学院和卫生系统。除了赠款资源外，该机构还提供近 1100 万美元/VR 的实物支持、费用分摊、试点和招募计划支持以及翻修费用，与 NIH 资金的比例超过 1:1。密歇根州的蓝十字蓝盾公司和辉瑞公司也进行了大量投资。各院系还贡献了超过 100 名 FTE 的潜在教职员工，以便 MICHR 可以为试点研究、K-12 和新的“迷你 K 项目”提供资助。这些汇总资源用于在现有的强大单位和项目以及关键临床和转化学科的学术项目的基础上创建强大的基础设施和支持，以提供教师领导、专业知识和咨询以及高质量的服务。这些项目涉及生物医学信息学、生物统计学、临床翻译、新方法、技术核心、社区参与、伦理、健康差异、儿科和监管支持。还描述了彻底重新配置的参与者和临床交互资源。这些项目都由一个教育项目联合起来，该项目覆盖了广泛的受众：从本科生到职业中期教职人员，从基础科学家到人口研究人员，从工作人员到社区成员。提供加速课程和强化课程。最后，一个强有力的试点计划将每年支付高达 800 万美元的试点资金，重点是刺激转化和跨学科研究。

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of Michigan Clinical and Translational Sciences Award (UM CTSA) will focus the formidable strengths of one of the world's finest research institutions on supporting and facilitating clinical and translational "team science". The UM CTSA will be housed in the newly created Michigan Institute of Clinical and Health Research (MICHR). MICHR was created by the University to maximize the potential of an institution that is extremely supportive of interdisciplinary research and has tremendous strengths in the health sciences. MICHR creates a partnership between relevant unit of the University, the NIH, external industry partners, and the community. The overwhelming majority of UM schools, colleges, and institutes are participating, including the top-ranked Schools of Business, Dentistry, Medicine, Nursing, Social Work, and Public Health, the Colleges of Engineering, Pharmacy, and Literature, Science and Arts, the Division of Kinesiology, the Institute of Social Research, and the Life Sciences Institute. The University-owned Health System, which includes integrated outpatient and inpatient facilities, is contributing significantly to a strong partnership with the UM CTSA. The Director of MICHR is the PI of the UM CTSA grant, and reports to a University Executive Vice President, who also oversees the Medical School and Health System. In addition to the grant resources, the institution is contributing nearly $11 million/vr of in-kind support, cost-sharing, support of pilot and recruitment programs, and renovation costs, a more than 1:1 match of NIH dollars. Blue Cross Blue Shield of Michigan and Pfizer are also making sizable investments. Departments are also contributing more than 100 FTE in potential faculty effort, so that MICHR can grant effort for pilot studies, K- 12, and new "mini-K programs". These aggregate resources are used to create robust infrastructure and support based on strong existing units and programs, as well as academic programs in key clinical and translational disciplines, to provide faculty leadership, expertise, and consultation as well as high quality services. These Programs are in Biomedical Informatics, Biostatistics, Clinical Translation, Novel Methods, Technical Cores, Community Engagement, Ethics, Health Disparities, Pediatrics, and Regulatory Support. A radically reconfigured Participant and Clinical Interactions Resource is also described. These programs are all united by an Education Program that reaches a wide spectrum of audiences: from undergraduates to mid-career faculty, from basic scientists to population researchers, from staff to community members. Both accelerated options and intensive programs are available. Finally, a robust pilot program will disburse up to $8 million/yr in pilot funds, focusing on stimulating translational and interdisciplinary studies.