CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

CTSA 儿科研究基础设施

• 批准号: 8173853
• 负责人: KENNETH J. PIENTA
• 金额: $ 99.71万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173853
• 关键词: Pediatric Research; Research Infrastructure

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The University of Michigan Clinical and Translational Sciences Award (UM CTSA) will focus the formidable strengths of one of the world's finest research institutions on supporting and facilitating clinical and translational "team science". The UM CTSA will be housed in the newly created Michigan Institute of Clinical and Health Research (MICHR). MICHR was created by the University to maximize the potential of an institution that is extremely supportive of interdisciplinary research and has tremendous strengths in the health sciences. MICHR creates a partnership between relevant unit of the University, the NIH, external industry partners, and the community. The overwhelming majority of UM schools, colleges, and institutes are participating, including the top-ranked Schools of Business, Dentistry, Medicine, Nursing, Social Work, and Public Health, the Colleges of Engineering, Pharmacy, and Literature, Science and Arts, the Division of Kinesiology, the Institute of Social Research, and the Life Sciences Institute. The University-owned Health System, which includes integrated outpatient and inpatient facilities, is contributing significantly to a strong partnership with the UM CTSA. The Director of MICHR is the PI of the UM CTSA grant, and reports to a University Executive Vice President, who also oversees the Medical School and Health System. In addition to the grant resources, the institution is contributing nearly $11 million/vr of in-kind support, cost-sharing, support of pilot and recruitment programs, and renovation costs, a more than 1:1 match of NIH dollars. Blue Cross Blue Shield of Michigan and Pfizer are also making sizable investments. Departments are also contributing more than 100 FTE in potential faculty effort, so that MICHR can grant effort for pilot studies, K- 12, and new "mini-K programs". These aggregate resources are used to create robust infrastructure and support based on strong existing units and programs, as well as academic programs in key clinical and translational disciplines, to provide faculty leadership, expertise, and consultation as well as high quality services. These Programs are in Biomedical Informatics, Biostatistics, Clinical Translation, Novel Methods, Technical Cores, Community Engagement, Ethics, Health Disparities, Pediatrics, and Regulatory Support. A radically reconfigured Participant and Clinical Interactions Resource is also described. These programs are all united by an Education Program that reaches a wide spectrum of audiences: from undergraduates to mid-career faculty, from basic scientists to population researchers, from staff to community members. Both accelerated options and intensive programs are available. Finally, a robust pilot program will disburse up to $8 million/yr in pilot funds, focusing on stimulating translational and interdisciplinary studies.

本分项目是CTSA供资的估计百分比，即 被用于广泛的研究领域(艾滋病研究、儿科研究或 临床试验)。列出的总成本仅是对CTSA金额的估计 用于这一研究领域的基础设施，而不是由 授予子项目或子项目工作人员的NCRR补助金。 密歇根大学临床和翻译科学奖(UM CTSA)将把世界上最好的研究机构之一的强大优势集中在支持和促进临床和翻译“团队科学”上。UM CTSA将设在新成立的密歇根临床与健康研究所(MICHR)。MICHR是由该大学创建的，目的是最大限度地发挥一个机构的潜力，该机构非常支持跨学科研究，并在健康科学方面拥有巨大的优势。MICHR在大学相关单位、国家卫生研究院、外部行业合作伙伴和社区之间建立了伙伴关系。绝大多数密歇根大学的学校、学院和研究所都参加了这项活动，其中包括顶尖的商业、牙科、医学、护理、社会工作和公共卫生学院，工程学院、药学学院和文学、科学和艺术学院，运动学系，社会研究所和生命科学研究所。大学拥有的卫生系统，包括综合门诊和住院设施，正在为与UM CTSA建立强有力的伙伴关系做出重大贡献。MICHR主任是UM CTSA赠款的PI，向一名大学执行副校长报告，该副校长也负责监督医学院和卫生系统。除了赠款资源，该机构还提供了近1100万美元/VR的实物支持、成本分担、对试点和招聘项目的支持以及翻新费用，这与NIH的资金比例超过了1：1。密歇根蓝十字蓝盾公司和辉瑞公司也在进行可观的投资。各系还在潜在的教员工作中贡献了超过100 FTE，以便MICHR能够为试点研究、K-12和新的“迷你K计划”提供努力。这些资源用于在强大的现有单位和项目以及关键临床和翻译学科的学术项目的基础上创建强大的基础设施和支持，以提供教师领导、专业知识和咨询以及高质量的服务。这些课程包括生物医学信息学、生物统计学、临床翻译、新方法、技术核心、社区参与、伦理学、健康差异、儿科学和监管支持。还描述了一个从根本上重新配置的参与者和临床交互资源。所有这些项目都由一个教育项目联合在一起，该项目覆盖了广泛的受众：从本科生到职业生涯中期的教师，从基础科学家到人口研究人员，从工作人员到社区成员。既有加速选项，也有强化计划。最后，一个强大的试点计划将每年支付高达800万美元的试点资金，重点放在刺激翻译和跨学科研究上。