Identifying drug targets in microbial pathogens using metabolomics

使用代谢组学识别微生物病原体中的药物靶点

• 批准号: nhmrc : 1059530
• 负责人: Prof Malcolm Mcconville
• 金额: $ 50.9万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-drug-targets-using-metabolomics/454764
• 关键词: Identifying; drug; targets; microbial; pathogens

Infectious diseases such as malaria, leishmaniasis and tuberculosis cause enormous morbidity and mortality worldwide. This proposal will utilize advanced analytical and genetic approaches to study the metabolism of the respective protozoan and bacteria agents as well as the associated host responses. These approaches will be used to develop novel therapeutic approaches and new analytical tools that can be applied to other infectious diseases

疟疾、利什曼病和肺结核等传染病在全世界造成巨大的发病率和死亡率。这项建议将利用先进的分析和遗传方法来研究原生动物和细菌各自的代谢以及相关的宿主反应。这些方法将被用于开发新的治疗方法和新的分析工具，可以应用于其他传染病