Ovarian anti-Mullerian hormone: what does it do in the normal ovary and why is it so high in polycystic ovary syndrome?

点击翻译按钮获取中文摘要

In the womb, boy babies develop part of their reproductive system because of the actions of a hormone called anti-Mullerian hormone (AMH). Interestingly, this hormone has now been shown to play a part in adult women in that it is involved in the working of the ovary. In the ovary each month an egg is grown and released. We have found that only those eggs which have got rid of AMH manage to grow. This is important because we have also found that the levels of this hormone are very high in a common condition which causes infertility. We now need to find out why the levels are high in these women and what exactly AMH does in the ovary. We hope that this will allow us to help these women to have better fertility in the future.