Informing Latinas About Medications To Reduce Risk For Breast Cancer

告知拉丁裔有关降低乳腺癌风险的药物

• 批准号: 8009542
• 负责人: Marielena Lara
• 金额: $ 148.71万
• 依托单位: RAND CORPORATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2013-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8009542
• 关键词: Informing; Latinas; About; Medications; Reduce

DESCRIPTION (provided by applicant): Significant disparities exist between the prevention and treatment of breast cancer among Latinas and non-Latina white women. An important factor appears to be the difference in access to evidence-based health information between these groups of women. Dissemination of language-, literacy-, and culturally appropriate prevention and treatment messages could reduce disparities in access to evidenced-based health information and preventive care for Latinas at risk for breast cancer. RAND Health, in collaboration with Olive View-UCLA Medical Center (OVMC), a Los Angeles County Department of Health Services hospital, proposes to develop and conduct a pilot evaluation of three alternative strategies to communicate patient-targeted messages related to the CER, "Comparative Effectiveness of Medications to Reduce Risk for Primary Breast Cancer in Women." The overall aim is to increase the use, impact, and implementation of the recommendations of this CER by adapting and testing innovative alternative strategies among Spanish-speaking women at risk for breast cancer. No consumer-oriented materials currently exist for this CER. This proposal has three specific aims: 1. To conduct formative research to develop language-, literacy-, culturally-, and content-appropriate evidence-based patient-oriented messages for the chosen CER. 2. To develop and pilot test the efficacy of three alternative prototypes (e.g., print media, community health worker, computer delivery) for the delivery of the messages in Spanish-speaking women. 3. To develop, in collaboration with AHRQ and other stakeholders, a plan to disseminate the results to promote the effectiveness and impact of the CER recommendations among Latina women at risk. To balance consumer-, clinical, and evidence-based perspectives, the project will employ a community advisory board of stakeholders, key informant interviews, and focus groups to assist in identifying and "translating" the key messages, identifying the optimal dissemination venues, and recruiting a population of high-risk women to test the vehicles. We define translation as adapting the language, literacy level, and cultural focus of the CER's evidenced-based recommendations to target the intended audience. The available dissemination materials for this CER topic are highly technical. Thus, for this initial project, we concentrate on evaluating the relative efficacy of the translated strategies using a multi-arm randomized control trial. An important part of our project will be to develop a dissemination plan that considers alternatives for scaling up of the intervention(s) that we find to be efficacious for future evaluation of their effectiveness in the real world. RAND Health has assembled an exceptional project team with skills and experience in the evidence review process, breast cancer prevention and treatment, health communication, bilingual and bicultural implementation and evaluation methods, as well as direct experience with the population of interest. PUBLIC HEALTH RELEVANCE: Lack of language-, literacy-, and culturally-appropriate evidenced-based information contributes to disparities in breast cancer health care and health between Latinas and non-Latina white women. The proposed project will pilot and compare three evidence- based patient-oriented educational prototypes targeting Latinas, for a potentially life- saving preventive treatment, and using alternative modes of delivery (print media, community health worker, computer delivery).

描述(由申请人提供)：在拉丁裔和非拉丁裔白人妇女中，乳腺癌的预防和治疗存在显著差异。一个重要因素似乎是这些妇女群体在获取循证健康信息方面的差异。传播语言、识字和文化上适当的预防和治疗信息，可以减少有乳腺癌风险的拉丁裔人在获得基于证据的卫生信息和预防性护理方面的差距。兰德健康公司与洛杉矶县卫生服务部门医院Olive View-UCLA医疗中心(OVMC)合作，提议开发并进行三种替代战略的试点评估，以传达与CER相关的以患者为目标的信息，即“药物的比较有效性，以降低女性原发性乳腺癌的风险。”总体目标是通过在有乳腺癌风险的西班牙语妇女中调整和测试创新的替代策略，增加本CER建议的使用、影响和实施。这个CER目前没有面向消费者的材料。这项建议有三个具体目标：1.进行形成性研究，为选定的CER开发语言、识字、文化和内容适当的循证患者导向的信息。2.开发和试行三种替代原型(例如，印刷媒体、社区保健工作者、计算机传递)在西班牙语妇女中传递信息的效力。3.与人权事务高级专员办事处和其他利益攸关方合作，制定一项传播成果的计划，以促进《消除对妇女一切形式歧视公约》各项建议在面临风险的拉丁裔妇女中的效力和影响。为了平衡消费者、临床和基于证据的观点，该项目将雇用一个由利益相关者、关键线人访谈和焦点小组组成的社区咨询委员会，以协助识别和“翻译”关键信息，确定最佳传播场所，并招募一群高危女性来测试车辆。我们将翻译定义为适应CER以证据为基础的建议的语言、识字水平和文化重点，以瞄准目标受众。关于这一CER专题的现有传播材料具有很高的技术性。因此，对于这个最初的项目，我们专注于使用多臂随机对照试验来评估翻译策略的相对有效性。我们项目的一个重要部分将是制定一个传播计划，该计划考虑扩大干预的替代方案(S)，我们认为这对未来在现实世界中评估其有效性是有效的。兰德健康组建了一支出色的项目团队，在证据审查过程、乳腺癌预防和治疗、健康沟通、双语和双文化实施和评估方法以及与相关人群的直接经验方面拥有技能和经验。 公共卫生相关性：缺乏语言、识字和文化上适当的循证信息，导致拉丁裔和非拉丁裔白人妇女在乳腺癌保健和健康方面存在差异。拟议的项目将试点和比较三种以拉丁裔为目标、可能挽救生命的预防性治疗和使用替代交付方式(印刷媒体、社区卫生工作者、计算机交付)的循证、面向患者的教育原型。