COBRE: UDE CORE INFRASTRUCTURE: SHARED FACILITIES

COBRE：UDE 核心基础设施：共享设施

• 批准号: 7959536
• 负责人: ABRAHAM M LENHOFF
• 金额: $ 38.02万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959536
• 关键词: Biotechnology; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Delaware; Engineering; Funding; Grant; Institutes; Institution; Membrane Proteins; Nature; Operative Surgical Procedures; Production; Proteins; Research; Research Infrastructure; Research Personnel; Resources; Source; United States National Institutes of Health; X-Ray Crystallography; bioimaging; college; graduate student

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The COBRE supports the operation of 4 core facilties that are quite diverse in their scope and nature. Two are located at the Delaware Biotechnology Institute (DBI), viz. the Protein Production Facility and the Bioimaging Core, and are administered within the larger set of cores operated by DBI, with Drs. Wu and Czymmek as the respective managers. The Protein Production Facility was funded by the original COBRE grant and is supported primarily by the present COBRE, but the Bioimaging Core is a much larger enterprise administered by DBI, of which the COBRE provides a relatively small fraction. The X-ray Crystallography Core is located in the labs of Dr. Brian Bahnson, the only macromolecular crystallographer on campus, and is supported by COBRE in recognition of the numerous researchers seeking structural information via the facilities there. The College of Engineering Biotechnology Core Facility is a fairly inexpensive operation that is managed locally within the College by Drs. Lenhoff and Robinson with the assistance of postdocs and graduate students.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 毛绒支持4个核心风格的操作，它们的范围和性质非常多样化。 两个位于特拉华州生物技术研究所（DBI），即。蛋白质生产设施和生物成像核心，并在DBI操作的较大核心内给药。 Wu和Czymmek作为各自的经理。 蛋白质生产设施由原始的毛拨款资助，主要由目前的毛病支持，但是生物成像核心是由DBI管理的较大企业，其中毛绒提供了相对较小的部分。 X射线晶体学核心位于Brian Bahnson博士的实验室，Brian Bahnson博士是校园上唯一的大分子晶体学家，并得到了Cobre的支持，以表彰众多通过那里的设施寻求结构信息的研究人员。 工程生物技术学院的核心设施是一项相当便宜的操作，由Drs在当地管理。 Lenhoff和Robinson在博士后和研究生的协助下。