COBRE: CORE B FUNCTIONAL GENOMICS CORE AT OUHSC

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 功能基因组学核心位于4,000平方米的英尺斯坦顿湖最先进的实验室。青年生物医学研究中心，第二阶段在OUHSC校园。 功能基因组学的核心继续提供基因组测序，微阵列分析和真实的时间PCR支持的研究人员在OUHSC和周围的校园，以及全国各地的校园。 在过去的一年中，该核心已经支持了至少六个以前资助或目前的COBRE研究人员以及其他几个在微阵列开发和分析及测序的微生物发病机理领域的研究人员的研究。 继续支持这些项目，并使用新购买的Applied Biosystems SOLiD测序仪进一步开发新的下一代测序应用（基因组重测序，从头测序，小RNA分析和全转录组分析）将是我们下一个项目年的持续重点。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Functional Genomics Core resides within a 4,000 sq. ft. state-of-the art laboratory in the Stanton L. Young Biomedical Research Center, phase II on the OUHSC campus. The Functional Genomics core has continued to offer genomic sequencing, microarray analysis and Real Time PCR support to researchers on the OUHSC and surrounding campuses as well as to campuses across the country. During the past year, the core has supported research for at least six previously funded or current COBRE investigators as well as several other established researchers in the field of microbial pathogenesis for microarray development and analysis and sequencing. Continued support of these projects, and further development of the new next generation sequencing applications (genome resequencing, de novo sequencing, small RNA profiling and whole transcriptome profiling) using the newly purchased Applied Biosystems SOLiD sequencer will be our continued focus for the next project year.