COBRE: CORE B FUNCTIONAL GENOMICS CORE AT OUHSC

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。机构发展奖(IDEA)计划的目的是通过支持教师发展和加强位于国家卫生研究院拨款总成功率历史最低的州的机构的研究基础设施，促进与健康相关的研究并提高研究人员的竞争力(RFA#RR-00-003)。因此，我们成立了生物医学研究卓越中心(COBRE)，以细菌-宿主相互作用的功能基因组/蛋白质组分析为主题。科布雷由一名由NIH资助的老牌调查员领导，包括三名新的调查员和一名老牌调查员，他们以前没有NIH R01支持的历史。这是一项全州范围的倡议，包括俄克拉荷马州的三个主要的公共支持的研究机构1)俄克拉荷马大学(OU)，2)俄克拉荷马大学健康科学中心(OUHSC)，3)俄克拉荷马州立大学(OSU)和俄克拉荷马医学研究基金会(OMRF)，一个位于OUHSC校园附近的私人研究机构。OUHSC功能基因组学支持核心配备了使用微阵列和高通量DNA测序执行基因表达谱分析的所有方面。该核心还支持其他Cobre核心的活动，特别是根据需要提供高通量寡核苷酸合成。此外，该核心将通过为其他OUHSC教师提供培训和技术支持来促进教师发展

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the Institutional Development Award (IDeA) Program is to foster health-related research and increase the competitiveness of investigators through support of faculty development and enhancement of the research infrastructure of institutions located in states with historically low aggregate success rates for grant awards from the NIH (RFA #RR-00-003). Thus, we have established a Center of Biomedical Research Excellence (COBRE), with the thematic focus of Functional Genomic/Proteomic Analysis of Bacterial-Host Interactions. The COBRE is headed by an established NIH-funded investigator and includes three new investigators and an established investigator who do not have a prior history of NIH R01 support. This is a state-wide initiative that includes the three major publicly-supported research institutions in the state of Oklahoma 1) the University of Oklahoma (OU), 2) the Oklahoma University Health Sciences Center (OUHSC), 3) Oklahoma State University (OSU) and the Oklahoma Medical Research Foundation (OMRF), a private research institute located near the OUHSC campus. The OUHSC functional genomics support core is equipped to perform all aspects of gene expression profiling using microarrays and high throughput DNA sequencing. The core also supports activities of the other COBRE cores, in particular the provision of high-throughput oligonucleotide synthesis, as needed. In addition, the core will spur faculty development by providing training and technical support to other OUHSC facult