COBRE: CORE B FUNCTIONAL GENOMICS CORE AT OUHSC

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。机构发展奖（IDeA）计划的目的是通过支持教师发展和加强位于历史上总成功率较低的州的机构的研究基础设施，促进与健康相关的研究，提高研究人员的竞争力（RFA #RR-00-003）。因此，我们建立了一个生物医学研究卓越中心（COBRE），以细菌-宿主相互作用的功能基因组/蛋白质组学分析为主题。COBRE由一名NIH资助的研究者领导，包括三名新的研究者和一名没有NIH R01支持历史的研究者。这是一项全州范围的倡议，包括俄克拉何马州的三个主要公共支持的研究机构1)俄克拉何马大学（OU）， 2)俄克拉何马大学健康科学中心（OUHSC）， 3)俄克拉何马州立大学（OSU）和俄克拉何马医学研究基金会（OMRF），一个位于俄克拉何马州立大学校园附近的私人研究机构。OUHSC功能基因组学支持核心配备使用微阵列和高通量DNA测序执行基因表达谱的各个方面。该核心还支持其他COBRE核心的活动，特别是根据需要提供高通量寡核苷酸合成。此外，该中心将通过为其他澳大师资提供培训和技术支持来促进教师的发展

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the Institutional Development Award (IDeA) Program is to foster health-related research and increase the competitiveness of investigators through support of faculty development and enhancement of the research infrastructure of institutions located in states with historically low aggregate success rates for grant awards from the NIH (RFA #RR-00-003). Thus, we have established a Center of Biomedical Research Excellence (COBRE), with the thematic focus of Functional Genomic/Proteomic Analysis of Bacterial-Host Interactions. The COBRE is headed by an established NIH-funded investigator and includes three new investigators and an established investigator who do not have a prior history of NIH R01 support. This is a state-wide initiative that includes the three major publicly-supported research institutions in the state of Oklahoma 1) the University of Oklahoma (OU), 2) the Oklahoma University Health Sciences Center (OUHSC), 3) Oklahoma State University (OSU) and the Oklahoma Medical Research Foundation (OMRF), a private research institute located near the OUHSC campus. The OUHSC functional genomics support core is equipped to perform all aspects of gene expression profiling using microarrays and high throughput DNA sequencing. The core also supports activities of the other COBRE cores, in particular the provision of high-throughput oligonucleotide synthesis, as needed. In addition, the core will spur faculty development by providing training and technical support to other OUHSC facult