COBRE: OUHSC: CORE D INFORMATICS CORE

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。机构发展奖（IDEA）计划的目的是促进健康相关的研究，并通过支持教师发展和加强机构的研究基础设施来提高研究人员的竞争力，这些机构位于历史上总体成功率较低的州。因此，我们已经建立了一个卓越的生物医学研究中心（COBRE），其主题重点是细菌-宿主相互作用的功能基因组/蛋白质组学分析。COBRE由NIH资助的研究人员领导，包括三名新研究人员和一名没有NIH R 01支持历史的研究人员。这是一项全州范围的倡议，包括俄克拉荷马州的三个主要公共支持的研究机构：1）俄克拉荷马州大学（University of Oklahoma），2）俄克拉荷马州大学健康科学中心（University Health Sciences Center，OUHSC），3）俄克拉荷马州州立大学（OSU）和俄克拉荷马州医学研究基金会（Medical Research Foundation，OMRF），一个位于OUHSC校园附近的私立研究机构。信息学核心设施提供必要的计算机硬件和软件支持，以协调本项目参与者所需的引物设计和挑选、图像处理和数据分析的各个方面。此外，信息学核心设施是计算机科学专业的学生获得生物信息学工作经验的机会，并与生物医学研究人员一起设计和实施新软件。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the Institutional Development Award (IDeA) Program is to foster health-related research and increase the competitiveness of investigators through support of faculty development and enhancement of the research infrastructure of institutions located in states with historically low aggregate success rates for grant awards from the NIH (RFA #RR-00-003). Thus, we have established a Center of Biomedical Research Excellence (COBRE), with the thematic focus of Functional Genomic/Proteomic Analysis of Bacterial-Host Interactions. The COBRE is headed by an established NIH-funded investigator and includes three new investigators and an established investigator who do not have a prior history of NIH R01 support. This is a state-wide initiative that includes the three major publicly-supported research institutions in the state of Oklahoma 1) the University of Oklahoma (OU), 2) the Oklahoma University Health Sciences Center (OUHSC), 3) Oklahoma State University (OSU) and the Oklahoma Medical Research Foundation (OMRF), a private research institute located near the OUHSC campus. The Informatics Core Facility provides the computer hardware and software support necessary for coordination of all aspects of primer design and picking, image processing, and data analysis required by participants of this project. In addition, the Informatics Core Facility is an opportunity for Computer Science students to gain experience working in bioinformatics and with biomedical research personnel to design and implement new software.