Identifying novel regulators of RNA receptor signalling to modulate viral innate immunity

鉴定新的 RNA 受体信号调节因子以调节病毒先天免疫

• 批准号: nhmrc : 541948
• 负责人: Dr James Vince
• 金额: $ 20.81万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identifying-novel-regulators-innate-immunity/115868
• 关键词: Identifying; novel; regulators; RNA; receptor

Viruses elicit a rapid immune response upon infection that is crucial for controlling viral spread and disease. Human cells detect viral molecules to coordinate the the production of anti-viral proteins. The aim of this research is to identify new genes that are essential for controlling the initial immune response to viral infection. This research will help us understand how virus infection can be controlled appropriately, and may lead to the development of new anti-viral therapeutics.

病毒在感染后会引起快速的免疫反应，这对于控制病毒传播和疾病至关重要。人类细胞检测病毒分子以协调抗病毒蛋白的生产。这项研究的目的是确定控制对病毒感染的初始免疫反应所必需的新基因。这项研究将帮助我们了解如何适当地控制病毒感染，并可能导致新的抗病毒疗法的发展。