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Interleukin-1? biology: mechanisms of regulation, activation and secretion

Interleukin-1? biology: mechanisms of regulation, activation and secretion
白细胞介素-1?
批准号:
nhmrc : 1101405
负责人:
Dr James Vince
金额:
$43.99万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

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中文摘要
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英文摘要
The protein called intelreukin-1 (IL-1) is required to fight off invading pathogens but more recently has been implicated as contributing to diverse diseases characterised by excessive inflammation, such as arthritis, gout, atherosclerosis and even cancer. This project aims to understand how IL-1 is made within cells and then activated to cause inflammation, which will enable these processes to be therapeutically targeted.
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会议论文
Cell Death and Inflammation
Cell Death and Inflammation
  • 批准号:
    nhmrc : GNT1141466
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $47.67万
  • 财政年份:
    2018
  • 负责人:
    Dr James Vince
  • 依托单位:
Regulation of interleukin-1? activation in inflammatory diseases
The role of cell death pathways in inflammation and pathogen infection
国内基金
海外基金
组蛋白乙酰化修饰ATG13激活自噬在牵张应力介导骨缝Gli1+干细胞成骨中的机制研究
  • 批准号:
    82370988
  • 项目类别:
    面上项目
  • 资助金额:
    48.00万元
  • 批准年份:
    2023
  • 负责人:
    经典
  • 依托单位:
Journal of Integrative Plant Biology
  • 批准号:
    31024801
  • 项目类别:
    专项基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2010
  • 负责人:
    贺萍
  • 依托单位:
Computational Methods for Analyzing Toponome Data