Understanding Alcohol Misuse, Abuse and Dependence in Young Adulthood

描述（由申请人提供）：拟议的研究旨在解释西雅图社会发展项目（SSDP）小组中成年青年（21至30岁）酗酒、酒精滥用和酒精依赖的发生和过程。SSDP是一项理论驱动的纵向研究，研究儿童和青少年健康、行为问题和亲社会发展的预测因素。SSDP小组是在1985年808名参与者在五年级时组成的。这些数据包括酒精使用和相关行为的纵向测量，21岁，24岁，27岁和30岁的DIS/DSM-IV诊断评估（包括酒精滥用和依赖），以及来自个人，家庭，学校，同伴和邻里因素和特征的多个报告者的多项测量。我们寻求三年的支持，以完成从10岁到30岁收集的12波数据的分析，这些数据来自西雅图高犯罪率社区的808名多种族城市青年的性别平衡SSDP小组。这个多信息数据库将使我们能够了解儿童和青少年饮酒模式与30岁之前的年轻人酗酒，酗酒和酒精依赖之间的关系。我们还试图确定儿童和青少年的社会发展因素，这些因素可能直接预测成人酗酒，酒精滥用和酒精依赖，或减轻儿童和青少年饮酒模式对这些年轻成年人的影响。此外，我们试图了解特定的生活事件在青年期的贡献，如进入和退出婚姻，父母，和工作，以及其他社会发展的影响，在青年期的酗酒和酒精滥用和依赖。例如，我们还将寻求理解为什么一些有酒精问题的年轻人在成年早期坚持使用，而其他人则停止使用问题酒精。这项研究提供了一个独特的和具有成本效益的机会，通过利用现有的纵向数据集，从10岁到30岁的发展，研究对酒精滥用和依赖的重要发展影响。这项研究将为那些为酒精滥用、酒精滥用和酒精依赖制定预防和治疗干预措施的人提供有用的信息。公共卫生相关性：这项拟议中的研究在西雅图社会发展项目小组中调查了成年年轻人（21至30岁）酗酒、酗酒和酒精依赖的发生和过程。该研究旨在了解儿童和青少年饮酒模式与30岁之前的年轻人酗酒、酒精滥用和酒精依赖之间的关系，以及社会发展因素在影响这些模式中的作用。这项研究将为那些为酒精滥用、酒精滥用和酒精依赖制定预防和治疗干预措施的人提供有用的信息。

DESCRIPTION (provided by applicant): The proposed study seeks to explain the occurrence and course of binge drinking, alcohol abuse and alcohol dependence in young adulthood (ages 21 to 30) in the Seattle Social Development Project (SSDP) panel. SSDP is a theory-driven, longitudinal study of child and adolescent predictors of health and behavior problems and prosocial development. The SSDP panel was constituted when 808 participants were in the 5th grade in 1985. The data include longitudinal measures of alcohol use and related behaviors, DIS/DSM-IV diagnostic assessments (including alcohol abuse and dependence) at ages 21, 24, 27, and 30, and multiple measures from multiple reporters of individual, family, school, peer, and neighborhood factors and characteristics. We seek three years of support to complete analyses of 12 waves of data collected from age 10 through age 30 from the gender-balanced SSDP panel of 808 multiethnic urban youths from high-crime neighborhoods in Seattle. This multi-informant database will allow us to understand the relationship between childhood and adolescent patterns of alcohol use and young adult binge drinking, alcohol abuse and alcohol dependence through age 30. We also seek to identify social development factors in childhood and adolescence that may directly predict adult binge drinking, alcohol abuse and alcohol dependence or moderate the effects of childhood and adolescent patterns of alcohol use on these young adult outcomes. Further we seek to understand the contribution of specific life events during young adulthood, such as entry into and exit from marriage, parenthood, and work, as well as other social development influences in young adulthood on binge drinking and alcohol abuse and dependence. For example, we will also pursue understanding why some young adults with alcohol problem use early in adulthood persist while others desist from problem alcohol use. The study offers a unique and cost-effective opportunity to examine important developmental influences on alcohol abuse and dependence in young adulthood by capitalizing on an existing longitudinal data set that spans development from age 10 through age 30. The study will provide information of use to those designing preventive and treatment interventions for alcohol misuse, alcohol abuse and alcohol dependence. PUBLIC HEALTH RELEVANCE: The proposed study examines the occurrence and course of binge drinking, alcohol abuse and alcohol dependence in young adulthood (ages 21 to 30) in the Seattle Social Development Project panel. The study seeks to understand the relationship between childhood and adolescent patterns of alcohol use and young adult binge drinking, alcohol abuse and alcohol dependence through age 30, and the role of social- developmental factors in influencing these patterns. The study will provide information of use to those designing preventive and treatment interventions for alcohol misuse, alcohol abuse and alcohol dependence.