THE CHANGING PATTERN OF RENAL BIOMARKERS IN CARDIAC CATHERIZATION

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们研究的最终目的是开发降低与急性肾损伤（阿基）相关的40-60%死亡率的方法。 目标1：描述在一项前瞻性队列研究中，60例在心导管插入术期间暴露于造影剂的患者中，肾损伤的既定和新型生物标志物的变化模式。 目的2：确定是否有比血清肌酐更好的阿基预测因子。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The ultimate aim of our research is to develop ways to reduce the 40-60% mortality rate associated with acute kidney injury (AKI). Aim 1: To describe the pattern of change of established and novel biomarkers of renal damage in a prospective cohort of 60 pilot study patients exposed to contrast during cardiac catheterization. Aim 2: To determine if there are better predictors of AKI than serum creatinine.