THE CHANGING PATTERN OF RENAL BIOMARKERS IN CARDIAC CATHERIZATION

心导管术中肾脏生物标志物的变化模式

• 批准号: 8166853
• 负责人: Ravindra L. Mehta
• 金额: $ 0.43万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166853
• 关键词: Acute Renal Failure with Renal Papillary Necrosis; Biological Markers; Cardiac; Cardiac Catheterization Procedures; Computer Retrieval of Information on Scientific Projects Database; Creatinine; Funding; Grant; Institution; Kidney; Patients; Pattern; Pilot Projects; Research; Research Personnel; Resources; Serum; Source; United States National Institutes of Health; cohort; mortality; novel; prospective

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The ultimate aim of our research is to develop ways to reduce the 40-60% mortality rate associated with acute kidney injury (AKI). Aim 1: To describe the pattern of change of established and novel biomarkers of renal damage in a prospective cohort of 60 pilot study patients exposed to contrast during cardiac catheterization. Aim 2: To determine if there are better predictors of AKI than serum creatinine.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们研究的最终目的是找到降低与急性肾损伤(AKI)相关的40%-60%死亡率的方法。 目的1：描述60例先导性研究患者在心导管置入术期间暴露于造影剂的前瞻性队列中已建立的和新的肾损害生物标志物的变化模式。 目的2：确定是否有比血肌酐更好的预测AKI的指标。