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ACUTE EFFECT OF COCOA ON CARDIOVASCULAR FUNCTION

ACUTE EFFECT OF COCOA ON CARDIOVASCULAR FUNCTION
可可对心血管功能的急性影响
批准号：
7951284
负责人：
KEVIN D MONAHAN
金额：
$2.54万
依托单位：
PENNSYLVANIA STATE UNIV HERSHEY MED CTR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2010-03-31
来源：
https://reporter.nih.gov/project-details/7951284
关键词：
AcuteCardiovascular PhysiologyClinical ResearchCocoa PowderComputer Retrieval of Information on Scientific Projects DatabaseDilatation - actionDoseElderlyFundingGrantIngestionInstitutionMediatingProtocols documentationResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healtharterial stiffnesscardiovascular risk factorimprovedmiddle ageresponse

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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该方案将首先探讨可可对血管内皮功能的剂量反应，其次是血流介导的扩张，其次是对中老年人动脉僵硬的影响。摄入可可与降低心血管风险有关，其机制尚不清楚，尽管有人提出了改善内皮功能的建议。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protocol will explore the dose response of cocoa on endothelial function primarily, flow mediated dilatation and secondarily, the effects on arterial stiffness on middle aged and older adults. Ingestion of cocoa has been associated with decreased cardiovascular risk and the mechanisms are unknown, though improved endothelial function is proposed.
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