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ACUTE EFFECT OF COCOA ON CARDIOVASCULAR FUNCTION

ACUTE EFFECT OF COCOA ON CARDIOVASCULAR FUNCTION
可可对心血管功能的急性影响
批准号：
7951284
负责人：
KEVIN D MONAHAN
金额：
$2.54万
依托单位：
PENNSYLVANIA STATE UNIV HERSHEY MED CTR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2010-03-31
来源：
https://reporter.nih.gov/project-details/7951284
关键词：
AcuteCardiovascular PhysiologyClinical ResearchCocoa PowderComputer Retrieval of Information on Scientific Projects DatabaseDilatation - actionDoseElderlyFundingGrantIngestionInstitutionMediatingProtocols documentationResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healtharterial stiffnesscardiovascular risk factorimprovedmiddle ageresponse

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本方案将探讨可可对内皮功能的剂量反应，主要是血流介导的扩张，其次是对中老年动脉僵硬度的影响。 摄入可可与降低心血管风险有关，尽管提出了改善内皮功能的机制尚不清楚。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protocol will explore the dose response of cocoa on endothelial function primarily, flow mediated dilatation and secondarily, the effects on arterial stiffness on middle aged and older adults. Ingestion of cocoa has been associated with decreased cardiovascular risk and the mechanisms are unknown, though improved endothelial function is proposed.
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