MECHANISMS UNDERLYING DECREASED VENOUS COMPLIANCE WITH AGE

静脉顺应性随年龄下降的机制

• 批准号: 7951303
• 负责人: KEVIN D MONAHAN
• 金额: $ 0.14万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951303
• 关键词: Adrenergic Agents; Age; Aging; Blood Circulation; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Limb structure; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; Venous; adrenergic

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Aging is associated with increased sympathetic activation as well as adrenergic tone in the arterial circulation. However, the role of adrenergic tone on decreased venous compliance associated with age is unknown. The aim of this current study is to determine the role of adrenergic tone on age associated decreases in limb venous compliance.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 衰老与交感神经激活增加以及动脉循环中的肾上腺素能张力有关。 然而，肾上腺素能紧张性在与年龄相关的静脉顺应性下降中的作用尚不清楚。 本研究的目的是确定肾上腺素能紧张性对年龄相关的肢体静脉顺应性下降的作用。