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LIMB NEUROVASCULAR CONTROL AND AGING: MSNA AND BLOOD FLOW

LIMB NEUROVASCULAR CONTROL AND AGING: MSNA AND BLOOD FLOW
四肢神经血管控制和衰老：MSNA 和血流
批准号：
7951250
负责人：
KEVIN D MONAHAN
金额：
$0.09万
依托单位：
PENNSYLVANIA STATE UNIV HERSHEY MED CTR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2010-03-31
来源：
https://reporter.nih.gov/project-details/7951250
关键词：
AgeBlood flowClinical ResearchComputer Retrieval of Information on Scientific Projects DatabaseElderlyFundingGrantHypovolemiaInstitutionLegLimb structureResearchResearch PersonnelResourcesRestSourceStressTestingUnited States National Institutes of HealthUpper armVasoconstrictor Agentsresponseyoung adult

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 中心，不一定是研究者的机构。 研究人员将检验这一假设，即静息和中枢血容量减少诱导的MSNA增加在老年人的手臂和腿部相似。研究人员还假设，与年轻人相比，分级中枢低血容量应激期间MSNA的增加与老年人手臂和腿部的血管收缩反应迟钝有关。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The investigators will test the hypothesis that resting and central hypovolemia-induced increases in MSNA are similar in the arm and leg of older adults. The investigators also hypothesize that increases in MSNA during graded central hypovolemic stress are associated with blunted vasoconstrictor responses in both the arm and leg of older compared to younger adults.
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