PHYSICAL ACTIVITY IN PREGNANCY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项拟议的研究的目的是测试积极的母亲，一种认知行为体力活动(PA)计划，以两种干预方式(半强度结构性锻炼和最小接触PA)提供的有效性，以增加妊娠期糖尿病(GDM)妇女的PA行为，并确定该计划对母婴结局的影响。由于妊娠期糖尿病增加了孕产妇/胎儿的发病率，并且与这些妇女及其子女在以后的生活中发生2型糖尿病有关，因此研究治疗和预防妊娠期糖尿病的干预措施至关重要。到目前为止，还没有研究以改善妊娠期糖尿病妇女的PA行为为主要目标进行干预，也没有研究考察母亲PA对妊娠/分娩并发症和婴儿结局的影响的研究有限。由于早期筛查程序，怀孕18周的妇女将被确认为妊娠期糖尿病。参与者将被随机接受结构化运动、生活方式PA或怀孕剩余时间的标准护理控制条件。所有参与者都将在怀孕期间接受一系列生物、心理和社会变量的多重评估。将获得医疗记录，以评估怀孕生物标志物、妊娠/分娩并发症和婴儿出生结果。主要结果是女性的PA行为(例如，平均计数/分钟、能量消耗、满足PA指南)。次要结果包括母亲PA对心理社会相关因素(例如，身体活动态度、自我效能、社会支持；抑郁、生活质量)、妊娠/分娩并发症(例如，母亲体重状况、是否需要胰岛素)和婴儿结局(例如，出生体重)的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this proposed research is to test the effectiveness of ACTIVE MOMS, a cognitive behavioral physical activity (PA) program, delivered as two interventions (semi-intensive structured exercise and minimum-contact PA), for increasing PA behaviors of women with gestational diabetes mellitus (GDM), and to determine the impact of this program on maternal/fetal outcomes. Because GDM increases maternal/fetal morbidity and it is associated with the onset of type 2 diabetes later in life for these women and their children, it is critically important that interventions be studied to treat and prevent GDM. To date, there are no studies that have intervened with GDM women with a primary objective of increasing their PA behaviors, and limited research examining the effects of maternal PA on pregnancy/delivery complications and infant outcomes. Women will be identified as having GDM by 18 weeks gestation as a result of early screening procedures. Participants will be randomized to receive either the structured exercise, lifestyle PA, or standard care control condition for the remainder of the pregnancy. All participants will undergo multiple assessments over their pregnancy on a series of biopsychosocial variables. Medical records will be obtained to assess pregnancy biomarkers, pregnancy/delivery complications, and infant birth outcomes. The primary outcome is women's PA behaviors (e.g., mean counts/min, energy expenditure, meeting PA guidelines). Secondary outcomes include the effects of maternal PA on psychosocial correlates (e.g., physical activity attitude, self-efficacy, social support; depression, quality of life), pregnancy/delivery complications (e.g., maternal weight status, need for insulin), and infant outcomes (e.g., birth weight.