PHYSICAL ACTIVITY IN PREGNANCY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项拟议研究的目的是测试ACTIVE MOMS的有效性，这是一种认知行为体力活动（PA）计划，作为两种干预措施（半密集结构化运动和最小接触PA）提供，以增加妊娠期糖尿病（GDM）妇女的PA行为，并确定该计划对母亲/胎儿结局的影响。由于GDM增加了母亲/胎儿的发病率，并且与这些妇女及其子女日后发生2型糖尿病有关，因此研究干预措施以治疗和预防GDM至关重要。到目前为止，还没有研究干预GDM妇女的主要目标是增加他们的PA行为，和有限的研究检查产妇PA对妊娠/分娩并发症和婴儿结局的影响。作为早期筛查程序的结果，女性将在妊娠18周时被确定为患有GDM。受试者将被随机分配接受结构化运动、生活方式PA或标准护理控制条件，以维持妊娠的剩余时间。所有参与者将在其妊娠期间接受一系列生物心理社会变量的多次评估。将获得医疗记录，以评估妊娠生物标志物、妊娠/分娩并发症和婴儿出生结局。主要结果是女性的PA行为（例如，平均计数/分钟，能量消耗，符合PA指南）。次要结果包括母体PA对心理社会相关因素的影响（例如，身体活动态度、自我效能、社会支持;抑郁、生活质量），妊娠/分娩并发症（例如，母亲体重状况，胰岛素需求），和婴儿结果（例如，出生体重）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this proposed research is to test the effectiveness of ACTIVE MOMS, a cognitive behavioral physical activity (PA) program, delivered as two interventions (semi-intensive structured exercise and minimum-contact PA), for increasing PA behaviors of women with gestational diabetes mellitus (GDM), and to determine the impact of this program on maternal/fetal outcomes. Because GDM increases maternal/fetal morbidity and it is associated with the onset of type 2 diabetes later in life for these women and their children, it is critically important that interventions be studied to treat and prevent GDM. To date, there are no studies that have intervened with GDM women with a primary objective of increasing their PA behaviors, and limited research examining the effects of maternal PA on pregnancy/delivery complications and infant outcomes. Women will be identified as having GDM by 18 weeks gestation as a result of early screening procedures. Participants will be randomized to receive either the structured exercise, lifestyle PA, or standard care control condition for the remainder of the pregnancy. All participants will undergo multiple assessments over their pregnancy on a series of biopsychosocial variables. Medical records will be obtained to assess pregnancy biomarkers, pregnancy/delivery complications, and infant birth outcomes. The primary outcome is women's PA behaviors (e.g., mean counts/min, energy expenditure, meeting PA guidelines). Secondary outcomes include the effects of maternal PA on psychosocial correlates (e.g., physical activity attitude, self-efficacy, social support; depression, quality of life), pregnancy/delivery complications (e.g., maternal weight status, need for insulin), and infant outcomes (e.g., birth weight.)