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A PHASE II/III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF URIDINE

A PHASE II/III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF URIDINE
尿苷 II/III 期、随机、双盲、安慰剂对照试验
批准号:
7951562
负责人:
Judith S. Currier
金额:
$2.06万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-04-01 至 2009-11-30

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者(PI)可能从另一个NIH来源获得了主要资金, 因此可以在其他CRISP条目中表示。所列机构为 研究中心,而研究中心不一定是研究者所在的机构。 具体目标: 主要目的: ¿¿ 通过比较尿苷组和安慰剂组之间DEXA(双能X线吸收测定法)测量的肢体脂肪从基线至第48周的变化,检查补充尿苷对临床脂肪萎缩的HIV-1感染受试者肢体脂肪的影响。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. SPECIFIC AIMS: Primary Objective: ¿¿ To examine the effect of uridine supplementation on limb fat in HIV-1-infected subjects with clinical lipoatrophy, by comparing changes from baseline to week 48 in DEXA (dual-energy x-ray absorptiometry)-measured limb fat between the uridine arm and placebo arm.
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